China Factory Direct
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| CAS number | 158401-00-4 |
| Product name | 2,2,2-trifluoro-1-(3,4,5-trichlorophenyl)ethanone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | High-efficiency insecticidal intermediate for synthesizing novel anthranilamide-class insecticides (e.g., flubendiamide) | Cyclization reaction with o-phenylenediamine derivatives to prepare the target insecticidal active ingredient |
| Pharmaceuticals | Potential pharmaceutical synthetic intermediate for constructing candidate molecules containing trifluoromethyl and polychlorinated aryl moieties | Participates in nucleophilic substitution, reductive amination, or metal-catalyzed coupling reactions to introduce specific pharmacophores |
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state, and presence of visible impurities. Typically appears as a white to off-white crystalline powder. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol/water or acetonitrile/water as the mobile phase. Detection is performed using a UV detector (e.g., 254 nm), and quantification is achieved via external or internal standard methods. |
| Purity Analysis | Gas Chromatography-Mass Spectrometry (GC-MS) or HPLC-DAD | GC-MS is used for identification and semi-quantification of volatile impurities; HPLC detects non-volatile impurities, allowing calculation of total impurity levels and individual impurity peaks. |
| Residual Solvents | Gas Chromatography (GC) | According to ICH guidelines, headspace sampling with GC-FID is used to detect common organic solvents such as methanol, ethanol, acetone, and dichloromethane. |
| Water Content | Karl Fischer Titration | Measures water content using coulometric or volumetric methods, suitable for organic intermediates with low moisture levels. |
| Melting Point | Melting Point Apparatus | Determined by capillary method or automatic melting point instrument to assess purity and consistency. The typical melting range for this compound is approximately 90–95°C (specific values may vary by literature). |
| Related Substances (Impurities) | HPLC Method | Impurity peaks are separated from the main peak using gradient elution. Impurity structures are confirmed using DAD or mass spectrometry, and individual impurity levels are evaluated against acceptance criteria. |
| Elemental Analysis (Chlorine, Fluorine) | Elemental Analyzer (CHNS/O Analyzer) or Ion Chromatography | Determines the content of elements such as C, H, N, F, and Cl to verify whether the molecular composition matches the theoretical values, used for structural confirmation. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Infrared absorption spectrum is obtained using KBr pellet method. Comparison with reference spectra confirms the presence of functional groups (e.g., carbonyl, C-F, C-Cl bonds). |
| Nuclear Magnetic Resonance (NMR) | ¹⁹F-NMR and ¹H-NMR | Used for structural confirmation. ¹⁹F-NMR detects signals from trifluoromethyl groups, while ¹H-NMR verifies aromatic protons and other structural features. Commonly applied in the identification of starting materials for active pharmaceutical ingredients. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.