3-Bromo-2-hydroxy-5-nitropyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 15862-33-6 |
| Product name | 3-Bromo-2-hydroxy-5-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Bromo-2-hydroxy-5-nitropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Bromo-2-hydroxy-5-nitropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Bromo-2-hydroxy-5-nitropyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of anti-infective drugs and active pharmaceutical ingredients (APIs) | Used as a key intermediate for constructing nitrogen-containing heterocyclic structures; employed in coupling reactions or nucleophilic substitution reactions to prepare target molecules |
| Agrochemicals | Synthesis intermediate for fungicides and herbicides | Participates in multi-step organic synthesis via its nitro and bromo functional groups to introduce the pyridine scaffold, thereby enhancing biological activity |
| Organic Synthesis | Multifunctional organic synthesis building block | Enables selective derivatization through the reactivity of its hydroxyl, bromo, and nitro groups for construction of complex molecular architectures |
Manufacturing Quality Control of 3-Bromo-2-hydroxy-5-nitropyridine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., isomers, nitro-reduction products, bromination by-products) relative to main peak using gradient elution. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., DMF, dichloromethane, methanol) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation in pyridine-free reagent; water reacts stoichiometrically with iodine and sulfur dioxide in methanol medium. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification after acid digestion; detection based on atomic emission intensity at characteristic wavelengths following plasma excitation. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection; chloride identified and quantified by retention time and peak area. |
| Sulfated Ash | Gravimetric Analysis | Sample incinerated at 700-800 C, residue treated with sulfuric acid and re-ignited; ash mass measured as percentage of original sample. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or via automated optical detection as solid transforms to liquid; reported as onset and clear point range. |
| Loss on Drying | Thermogravimetric Analysis (TGA) | Mass loss measured under controlled heating (e.g., 105 C, 2 h) in air or nitrogen; reflects volatile content including residual solvents and moisture. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Electrode-based measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water), indicating acidic/basic decomposition products. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered light intensity patterns from dispersed particles in liquid medium to calculate volume-based size distribution (D10, D50, D90). |
| Organic Volatile Impurities (OVI) | GC-MS | Identification and quantification of structurally undefined volatiles using mass spectral library matching and selected ion monitoring after headspace sampling. |
Technical Specifications of 3-Bromo-2-hydroxy-5-nitropyridine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148-152°C |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Bromo-2-hydroxy-5-nitropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Bromo-2-hydroxy-5-nitropyridine
Safety Information of 3-Bromo-2-hydroxy-5-nitropyridine
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 3-Bromo-2-hydroxy-5-nitropyridine
Industrial 3-Bromo-2-hydroxy-5-nitropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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