China Factory Direct
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| CAS number | 1588441-34-2 |
| Product name | 4-Methylbenzenesulfinic acid hydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key chiral building block for the synthesis of the antiplatelet drug ticagrelor | Acts as a chiral auxiliary in asymmetric sulfonylation; the resulting product undergoes subsequent coupling and cyclization to form the thienopyrimidine core of ticagrelor |
| Agrochemical Intermediates | Pre-sulfonylating precursor for synthesizing novel sulfonylurea herbicides | Undergoes nucleophilic substitution with amines under basic conditions to construct the sulfonylurea bridge |
| Organic Synthesis | Chiral sulfinyl salt ligand precursor for transition-metal-catalyzed asymmetric reactions | Converted via reduction or alkylation to chiral sulfoximines or sulfinates, applied in Pd/Cu-catalyzed C–S bond formation and asymmetric oxidation reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (p-Toluenesulfinic acid monohydrate content) | Acid-base titration with standardized NaOH | Quantifies active compound by neutralizing acidic protons using phenolphthalein endpoint detection. |
| Water content | Karl Fischer titration | Measures total water via iodine-sulfur dioxide redox reaction in anhydrous methanol medium. |
| Heavy metals (Pb, Cd, Hg, As) | ICP-MS | Simultaneously quantifies trace metal impurities after acid digestion and nebulization into plasma. |
| Residual solvents (e.g., ethanol, acetone) | Gas chromatography (GC-FID) | Separates and detects volatile organic solvents based on retention time and flame ionization response. |
| Chloride impurity | Ion chromatography (IC) | Separates and quantifies chloride ions using suppressed conductivity detection after anion exchange. |
| Sulfate impurity | Barium sulfate gravimetric method | Precipitates sulfate as BaSO4 and determines mass after drying and weighing. |
| Related substances (impurity profiling) | HPLC-UV | Separates structurally similar compounds using reversed-phase C18 column and UV detection at 254 nm. |
| Appearance (color and physical state) | Visual inspection | Assesses color, crystallinity, and presence of foreign particles under controlled white light. |
| Melting point | Capillary melting point apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary tube method. |
| pH of aqueous solution (1% w/v) | pH meter measurement | Measures hydrogen ion activity in a standardized aqueous suspension using calibrated glass electrode. |
| Loss on drying (LOD) | Thermogravimetric analysis (TGA) | Quantifies volatile loss (including hydrate water) by measuring mass change upon heating to 105 C under nitrogen. |
| Iron content | Atomic absorption spectroscopy (AAS) | Measures Fe concentration via absorption of specific wavelength light by ground-state Fe atoms in flame atomizer. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 125.0–129.0°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Odor | Characteristic mild sulfurous odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.