4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 159191-56-7 |
| Product name | 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Used as a key intermediate in the synthesis of targeted anticancer agents (e.g., BTK inhibitors) and anticoagulants | Applied in Suzuki-Miyaura cross-coupling reactions |
| Materials Science | Used to prepare functional materials for hole-transport layers in organic light-emitting diodes (OLEDs) | Applied in palladium-catalyzed arylations to construct conjugated frameworks |
| Pesticide R&D | Employed as a structural modification unit in structure–activity relationship studies of novel insecticidal molecules | Applied in selective couplings under pinacol boronate protection/deprotection strategies |
Manufacturing Quality Control of 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., THF, toluene, methanol) against calibrated standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine-based reagent to determine trace water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and Ni after acid digestion, using plasma emission spectroscopy against matrix-matched calibration curves. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue remaining after high-temperature ashing (700-800 C) to assess inorganic impurities. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against NaCl calibration standards. |
| Acid Value | Acid-Base Titration | Titration with standardized NaOH solution using phenolphthalein indicator to determine free carboxylic or boronic acid equivalents. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically during controlled heating; used for identity and purity assessment. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser scattering to determine D10, D50, D90 values per USP <429>. |
| Appearance | Visual Inspection | Assessment of color and physical state (crystalline powder) against established reference standard under controlled lighting. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light through a solution to confirm chiral integrity and identity (if applicable). |
Technical Specifications of 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
Safety Information of 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID
Industrial 4-(TERT-BUTYLDIMETHYLSILYLOXY)PHENYLBORONIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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