N4-Acetyl-2'-Fluoro-2'-deoxycytidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 159414-97-8 |
| Product name | N4-Acetyl-2'-Fluoro-2'-deoxycytidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for N4-Acetyl-2'-Fluoro-2'-deoxycytidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk N4-Acetyl-2'-Fluoro-2'-deoxycytidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of N4-Acetyl-2'-Fluoro-2'-deoxycytidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Antiviral drug candidate for treating DNA virus–related diseases, including herpesviruses and hepatitis B virus | Used as a nucleoside analog; phosphorylated intracellularly by kinases to the triphosphate form, competitively inhibiting viral DNA polymerase activity and incorporating into viral DNA to cause chain termination |
| Biomedical Research | Molecular probe for studying viral replication mechanisms and host-cell nucleotide metabolism | Applied in in vitro cell culture models; antiviral DNA synthesis inhibition and cytotoxicity are assessed using qPCR, Western blot, and related techniques |
| Medicinal Chemistry | Lead compound for structural optimization of novel nucleoside-based antiviral agents | Used to conduct structure–activity relationship (SAR) studies based on its 2′-fluoro and N4-acetyl structural features; employed to design and synthesize derivative series aimed at improving selectivity, metabolic stability, and oral bioavailability |
Manufacturing Quality Control of N4-Acetyl-2'-Fluoro-2'-deoxycytidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 260 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient reversed-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of organic solvents (e.g., methanol, acetone, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric titration based on the reaction of iodine with water in a pyridine-methanol buffer under controlled conditions. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectroscopy. |
| Optical Rotation | [alpha]D Measurement | Determination of specific rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm stereochemical integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing the temperature range over which solid-to-liquid phase change occurs. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular variation of laser light scattering intensity. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens following USP <61> and <62>. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode and pH meter. |
Technical Specifications of N4-Acetyl-2'-Fluoro-2'-deoxycytidine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 195–199 °C |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | -15.0 to -19.0° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of N4-Acetyl-2'-Fluoro-2'-deoxycytidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of N4-Acetyl-2'-Fluoro-2'-deoxycytidine
Safety Information of N4-Acetyl-2'-Fluoro-2'-deoxycytidine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of N4-Acetyl-2'-Fluoro-2'-deoxycytidine
Industrial N4-Acetyl-2'-Fluoro-2'-deoxycytidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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