FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 159610-93-2 |
| Product name | FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Protecting reagent for serine residues in solid-phase peptide synthesis (SPPS) | Used as a dual-protecting monomer for the side-chain hydroxyl and α-amino groups of serine in Fmoc-based SPPS; incorporated into the peptide chain via standard coupling reagents (e.g., DIC/HOBt or HATU/DIEA); the Fmoc group is removed under mild conditions using piperidine/DMF, while the O-methyl protection is cleaved concurrently during final TFA-mediated resin cleavage |
| Pharmaceutical R&D | Intermediate for therapeutic peptides containing serine (e.g., hormone analogs, antimicrobial peptides) | Employed to construct peptide lead compounds containing serine sequences where side-chain side reactions must be suppressed; enables high-purity, high-yield linear peptide assembly and subsequent cyclization or modification |
| Organic Synthesis | Chiral building block for constructing complex molecules containing β-hydroxy amino acids | Serves as a chiral template in asymmetric alkylation, oxidation, or coupling reactions; the O-methyl protecting group enhances hydroxyl stability, facilitating selective functional group transformations followed by deprotection |
Manufacturing Quality Control of FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 265 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities using gradient reversed-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of residual solvents (e.g., DMF, DCM, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content based on stoichiometric reaction. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Multi-element quantification of heavy metals (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma optical emission spectrometry. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of palladium residues (from coupling catalysts) using inductively coupled plasma mass spectrometry. |
| Particle Size Distribution | Laser Diffraction | Determination of particle size distribution in dry powder form using Mie scattering theory and laser diffraction analysis. |
| Loss on Drying | Thermogravimetric Analysis | Mass loss measurement upon heating under controlled conditions to assess volatile content and residual solvents. |
| Chloride Content | Ion Chromatography | Quantification of chloride ions using suppressed conductivity detection after anion exchange separation. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens using membrane filtration followed by culture on selective media. |
| pH of Solution | Potentiometric pH Measurement | Determination of pH in aqueous suspension (1% w/v) using calibrated glass electrode and pH meter. |
Technical Specifications of FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | +22±2.5° (c=1, in DMF) |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID
Safety Information of FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID
Industrial FMOC-(S)-2-AMINO-3-METHOXYPROPIONIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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