China Factory Direct
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| CAS number | 159766-56-0 |
| Product name | Fmoc-N'-Acetyl-L-lysine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Protective amino acid in synthetic peptide chains | Applied in solid-phase peptide synthesis |
| Cosmetics | Active ingredient in anti-aging products | Formulated by blending with other active ingredients |
| Research Reagents | Peptide research and development | Used in laboratory-scale peptide synthesis experiments |
| Food Industry | Functional food additive | Microencapsulated or directly incorporated into formulations |
| Test Item | Common Testing Methods | Method Overview |
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| Appearance and Character | Visual Inspection + Physical Property Recording | Observe sample color, state (white to off-white crystals or powder), odor, solubility, etc., in accordance with pharmacopoeial or internal corporate standards. |
| Identification | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with acetonitrile-water (containing 0.1% trifluoroacetic acid) as the mobile phase; compare retention time with reference standard to confirm consistency of the main peak. |
| Infrared Spectroscopy (IR) | Acquire the sample's infrared absorption spectrum and compare characteristic absorption peaks (e.g., Fmoc carbonyl at 1720 cm⁻¹, amide I/II bands) with the standard reference spectrum. | |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR / ¹³C-NMR) | Dissolve in DMSO-d₆ or CDCl₃ and analyze characteristic proton peaks (e.g., Fmoc aromatic protons, Nε-acetyl methyl, α-CH) to confirm structural integrity. | |
| Purity (Active Ingredient Content) | HPLC-UV / HPLC-ELSD | Determine the main peak area percentage using area normalization or external standard method; require ≥98.0% (adjustable based on application), and quantify total impurity peak areas. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace sampling to detect residual common synthesis solvents such as ethanol, acetonitrile, dichloromethane, and DMF, ensuring compliance with ICH Q3C limits. |
| Water Content | Karl Fischer Titration (KF) | Determine water content using coulometric or volumetric methods; typically control to ≤0.5% (for dry products) or ≤1.0%. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Digest the sample and determine levels of heavy metals such as lead, cadmium, mercury, arsenic, and copper; comply with pharmacopoeial limits (e.g., EP/USP, ≤10 ppm). |
| Chlorides/Sulfates | Turbidimetry or Ion Chromatography | Measure chloride ions via silver nitrate turbidimetry and sulfate ions via barium chloride turbidimetry to control inorganic impurity levels. |
| Amino Acid Composition and Chiral Purity | Amino Acid Analyzer (HPLC-OPA/FMOC) | After acid hydrolysis and derivatization, determine the proportion of L-lysine and confirm absence of racemization (compare with L-lysine reference standard). |
| Related Substances (Impurity Profile) | HPLC Gradient Elution Method | Develop a gradient method to separate degradation products (e.g., de-Fmoc compound, N-acetyl hydrolysis products, dimers); quantitatively control individual impurities ≤0.5%, total impurities ≤1.0%. |
| Solubility | Shake-Flask Method / Quantitative Solubility Method | Determine saturation solubility in solvents such as water, ethanol, DMSO, and DMF for use in process development and formulation reference. |
| Melting Point | Melting Point Apparatus | Measure the melting range (typical range: 120–128°C) and compare with literature values to assess crystalline form consistency. |
| Microbial Limits (if applicable) | Plate Count Method / MPN Method | For sterile or injectable-grade raw materials, test for total aerobic microbial count, mold and yeast, and Escherichia coli; comply with pharmacopoeial requirements for non-sterile products. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -17.0 to -15.0 deg (c=1, in 1M HCl) |
| Melting Point | 168 to 172 °C |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.