7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 160129-45-3 |
| Product name | 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antidepressant and anxiolytic drugs (e.g., SSRIs such as paroxetine) | Organic synthesis, catalytic hydrogenation |
| Drug Discovery | Molecular structure modification and activity screening for novel neuropharmacological agents | High-throughput screening, structural optimization |
| Fine Chemicals | Chemical building block for synthesizing heterocyclic compounds or functional materials | Multi-step synthesis, purification (e.g., crystallization) |
Manufacturing Quality Control of 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 220-254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification via retention time matching and threshold-based reporting per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify specified organic solvents based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to determine water content by stoichiometric reaction with Karl Fischer reagent. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using mass spectrometry for high sensitivity and selectivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic residue after controlled incineration at 700-800 C, expressed as percentage of initial sample weight. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, indicating crystallinity and identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution in suspension using Mie scattering theory and optical detection. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of hydrogen ion activity in a standardized aqueous suspension using calibrated glass electrode. |
| Microbial Limits | Membrane Filtration | Quantitative enumeration of aerobic microorganisms and detection of specified pathogens per USP <61> and <62>. |
Technical Specifications of 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE
Safety Information of 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE
Industrial 7-CHLORO-1,2,3,4-TETRAHYDRO-BENZO[B]AZEPIN-5-ONE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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