2-(1H-Pyrazol-1-yl)acetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16034-48-3 |
| Product name | 2-(1H-Pyrazol-1-yl)acetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-(1H-Pyrazol-1-yl)acetic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-(1H-Pyrazol-1-yl)acetic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-(1H-Pyrazol-1-yl)acetic acid
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate for the fungicide fluxapyroxad | Used to construct the pyrazole amide backbone via Ullmann coupling or analogous coupling reactions with halogenated arenes such as 2-chloropyridine |
| Pharmaceuticals | Used in the synthesis of pyrazole derivatives exhibiting anti-inflammatory and antitumor activity | Serves as a starting material for drug molecules containing the pyrazoleacetic acid structural motif, modified via amidation, esterification, or coupling reactions |
| Organic Synthesis | Multifunctional pyrazole-based building block for introducing 1-substituted pyrazoleacetic acid structures | Derivatized via carboxyl group activation (e.g., conversion to acyl chloride with SOCl₂) followed by reaction with amines or alcohols, or via decarboxylation, metalation, and other functionalization reactions |
Manufacturing Quality Control of 2-(1H-Pyrazol-1-yl)acetic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210-220 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., pyrazole, chloroacetic acid, ester derivatives) relative to main peak using gradient HPLC-UV. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of water with iodine and sulfur dioxide in a pyridine/methanol medium. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing (700-800 C) and weighing. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion and plasma emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions following aqueous extraction and filtration. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic sulfate residue after ignition with sulfuric acid treatment and final weighing. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via capillary tube observation under controlled heating rate (1-2 C/min). |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light (589 nm) in solution to assess chiral purity (if applicable as enantiomer). |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Determination of hydrogen ion activity using calibrated glass electrode in a standardized aqueous suspension. |
| Organic Volatile Impurities (Residual Solvents) | GC-FID | Identification and quantification of solvents (e.g., methanol, acetone, ethyl acetate) using gas chromatography with flame ionization detection. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against standard references under controlled lighting conditions. |
Technical Specifications of 2-(1H-Pyrazol-1-yl)acetic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-(1H-Pyrazol-1-yl)acetic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-(1H-Pyrazol-1-yl)acetic acid
Safety Information of 2-(1H-Pyrazol-1-yl)acetic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2-(1H-Pyrazol-1-yl)acetic acid
Industrial 2-(1H-Pyrazol-1-yl)acetic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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