China Factory Direct
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| CAS number | 160347-90-0 |
| Product name | BOC-D-PYR-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Peptide drug synthesis | As a derivative of D-pyroglutamic acid, used to incorporate D-pyroglutamic acid residues in solid-phase peptide synthesis (SPPS) or solution-phase synthesis for constructing peptide drug molecules with defined stereochemistry. |
| Pharmaceutical Chemicals | Synthesis of pharmaceutical intermediates | As a key chiral building block for synthesizing active pharmaceutical ingredients (APIs) containing the D-pyrrolidone carboxylic acid motif, such as specific antibiotics or peptide-based inhibitors. |
| Research Reagents | Peptide structural studies | Used to synthesize peptide reference standards or model compounds to investigate the effect of D-amino acids on secondary structure features (e.g., folding, stability) of peptide chains. |
| Biotechnology | Protecting group strategy | Leverages the reversible protection of amino groups by the Boc (tert-butoxycarbonyl) group to enable selective deprotection and functionalization in complex organic synthesis routes. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., ethyl acetate, toluene) by gas chromatography with flame ionization detection using internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Optical Rotation | [alpha]D | Measures specific rotation using sodium D-line light in a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies total heavy metals (Pb, Cd, Hg, As, etc.) after acid digestion by inductively coupled plasma optical emission spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Determines inorganic ash content by high-temperature incineration followed by weighing of residual non-volatile matter. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| pH of Aqueous Solution | Potentiometric Titration | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution by measuring angular scattering pattern of laser beam passing through dispersed sample. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms and specified pathogens (e.g., E. coli, S. aureus) by filtration, culture, and colony enumeration. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation of phase change. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=99.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | [α]22/D +34 to +36 |
| Total Impurities | <=1.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.