Ethyl 2,6-dichloroisonicotinate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1604-14-4 |
| Product name | Ethyl 2,6-dichloroisonicotinate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Ethyl 2,6-dichloroisonicotinate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Ethyl 2,6-dichloroisonicotinate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Ethyl 2,6-dichloroisonicotinate
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of the fungicide azoxystrobin | Used to prepare azoxystrobin via condensation, cyclization, and related steps with pyrimidinamine compounds |
| Pesticides | Intermediate in the synthesis of the insecticide flonicamid | Applied to construct the flonicamid molecular scaffold through hydrolysis, amidation, and related reactions |
| Pharmaceuticals | Potential synthetic intermediate for active molecules containing a chloroisonicotinic acid moiety | Employed as a structural modification unit in candidate compounds for anticancer and anti-inflammatory applications, participating in coupling or functional group transformation reactions |
Manufacturing Quality Control of Ethyl 2,6-dichloroisonicotinate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~220 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities (e.g., 2,6-dichloroisonicotinic acid, ethyl alcohol, unreacted intermediates) using gradient HPLC-UV. |
| Residual Solvents (Ethanol, Ethyl Acetate, Toluene) | GC-FID | Headspace gas chromatography with flame ionization detection, calibrated against solvent standards per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine–sulfur dioxide reaction in anhydrous methanol-based medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification after microwave-assisted acid digestion, offering sub-pptr detection limits per ICH Q3D. |
| Chloride Content | Potentiometric Titration with AgNO₃ | Direct titration using silver nitrate; endpoint detected by silver-ion-selective electrode based on formation of AgCl precipitate. |
| Acid Value | Acid-Base Titration (NaOH in ethanol) | Neutralization of residual acidic impurities (e.g., free acid) with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint. |
| Appearance & Color | Visual Inspection / APHA Color Scale | Comparison of sample solution (in specified solvent, e.g., acetone) against platinum-cobalt standard solutions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using calibrated digital melting point instrument per USP <741>. |
| Residue on Ignition | Gravimetric Analysis (Sulfated Ash) | Ignition at 700–800 °C followed by weighing of non-volatile inorganic residue after sulfuric acid treatment. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using Mie theory to determine volume-based particle size distribution (D10, D50, D90). |
Technical Specifications of Ethyl 2,6-dichloroisonicotinate
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 82.0-86.0°C |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Ethyl 2,6-dichloroisonicotinate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Ethyl 2,6-dichloroisonicotinate
Safety Information of Ethyl 2,6-dichloroisonicotinate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Ethyl 2,6-dichloroisonicotinate
Industrial Ethyl 2,6-dichloroisonicotinate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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