China Factory Direct
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| CAS number | 161024-80-2 |
| Product name | (R)-N-Boc-3-Amino-3-phenylpropanoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral building block for synthesizing β-amino acid-containing drug molecules, including antiviral agents, anticancer agents, and peptide-based therapeutics | Participates in amide bond formation following Boc deprotection, enabling construction of the target molecule’s chiral center in solid-phase or solution-phase peptide synthesis |
| Biopharmaceutical R&D | Applied in developing novel β-peptides and peptidomimetics to study structure–activity relationships and biological activity | Extended in peptide chain assembly using standard Fmoc/Boc strategies, leveraging its (R)-configuration to control secondary structures (e.g., helices, folds) |
| Chemical Synthesis | Employed as a chiral auxiliary or intermediate in asymmetric synthesis for constructing complex natural products or functional molecules | Introduced with defined stereochemistry via palladium-catalyzed coupling, reductive amination, or enzymatic resolution |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separates (R)- and (S)-enantiomers on a chiral stationary phase and calculates ee from peak area ratio. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric titration with iodine generated electrochemically in pyridine-methanol solvent. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., ethyl acetate, toluene) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separates and quantifies sulfate ions using anion-exchange column and suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Measures palladium residue after microwave digestion using inductively coupled plasma optical emission spectroscopy. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of visible particulates against a white background under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measures angle of rotation of plane-polarized light in solution to confirm chiral identity and enantiopurity. |
| pH of Aqueous Suspension | pH Meter | Measures pH of a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode per EP 2.2.3. |
| Test Item | Specification |
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| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Optical Rotation | +46.0 to +47.0° (c=1, in 1M HCl) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128 to 132°C |
| Identification (NMR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.