pyridine-3-sulfonyl chloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16133-25-8 |
| Product name | pyridine-3-sulfonyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for pyridine-3-sulfonyl chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk pyridine-3-sulfonyl chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of pyridine-3-sulfonyl chloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in drug synthesis for preparing kinase inhibitors, antitumor compounds, etc. | Used as a sulfonylation reagent in organic synthesis to produce sulfonamide derivatives via reaction with amines |
| Agrochemicals | Active ingredient or intermediate in herbicide and insecticide synthesis | Introduces the sulfonyl chloride group via nucleophilic substitution to modify molecular structure and enhance biological activity |
| Materials Science | Preparation of functionalized polymers or surface modifiers | Acts as a coupling agent to introduce the pyridylsulfonyl group via reaction with amino-containing materials |
| Research Reagents | Functional group transformation or molecular probe synthesis in chemical research | Carried out at laboratory scale for sulfonamide formation, sulfonate esterification, and related reactions |
Manufacturing Quality Control of pyridine-3-sulfonyl chloride
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, physical state (such as white to pale white crystalline powder), and presence of visible impurities. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically at 254 nm). Qualitative analysis is based on retention time, while quantitative analysis uses area normalization or external standard method for main component purity. |
| Content Determination | Titration (Hydrolysis followed by Acid-Base Titration) | Hydrolyze the sample to generate sulfonic acid, then titrate the resulting acid with a standard NaOH solution to calculate the effective content. Suitable for routine batch testing. |
| Moisture | Karl Fischer Titration (Karl Fischer) | Quantitatively react the moisture in the sample with KF reagent, and determine the moisture content by potentiometric titration. Suitable for trace moisture detection. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (such as methanol, ethanol, dichloromethane) during production according to ICH guidelines, using FID detector. |
| Melting Point | Melting Point Apparatus Method | Determine the initial and final melting points using an automatic or capillary melting point apparatus, to assess purity and crystal form consistency. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Separate the main peak and impurity peaks using gradient elution, and detect and quantify synthetic by-products or degradation products (such as sulfonic acid, unreacted raw materials). |
| Chlorine Content | Ion Chromatography or Oxygen Bottle Combustion - Silver Quantitation Method | Decompose the sample by oxygen bottle combustion to release chloride ions, which are then titrated with standard silver nitrate solution; alternatively, Cl⁻ content is determined by ion chromatography to verify structural integrity. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Perform pellet or ATR measurement on the sample, and compare with standard spectra to confirm the presence of functional groups (such as S=O, C-Cl, pyridine ring). |
| Nuclear Magnetic Resonance (NMR) | ¹H-NMR and ¹³C-NMR | Determine hydrogen and carbon spectra in deuterated solvent (such as DMSO-d6), used for structural confirmation and impurity analysis to ensure correct synthesis of the target compound. |
Technical Specifications of pyridine-3-sulfonyl chloride
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 45-49°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of pyridine-3-sulfonyl chloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of pyridine-3-sulfonyl chloride
Packaging of pyridine-3-sulfonyl chloride
Industrial pyridine-3-sulfonyl chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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