1-(Methanesulfonyl)-piperazine / 1-(Methanesulfonyl)-piperazine monohydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 161357-89-7 |
| Product name | 1-(Methanesulfonyl)-piperazine / 1-(Methanesulfonyl)-piperazine monohydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 161357-89-7
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 161357-89-7 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 161357-89-7
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for the antifungal drug voriconazole | Used as a chiral auxiliary in constructing the chiral center on the triazole ring side chain of voriconazole, introducing optical activity via asymmetric synthesis or chiral resolution |
| Pharmaceuticals | Structural modification unit for novel anticancer candidate compounds | Applied to modify the sulfonamide side chain of nitrogen-containing heterocyclic lead compounds to enhance target selectivity and metabolic stability; commonly employed in late-stage functionalization during medicinal chemistry optimization |
Manufacturing Quality Control of 161357-89-7
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Piperazine content) | Acid-Base Titration with HCl standard solution | Quantifies the main active ingredient by neutralizing the basic piperazine moiety with standardized hydrochloric acid. |
| Related Substances | HPLC with UV detection | Separates and quantifies structurally related impurities using reversed-phase chromatography and UV absorbance detection. |
| Residual Solvents | Gas Chromatography (GC) with FID | Detects and quantifies volatile organic solvents based on retention time and flame ionization response. |
| Water Content | Karl Fischer Titration | Determines trace water by electrochemical titration using iodine, sulfur dioxide, and a base in methanol. |
| Heavy Metals | ICP-OES | Measures total heavy metal content (e.g., Pb, Cd, Ni, Fe) via atomic emission spectroscopy after acid digestion. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Sulfate Impurity | Ion Chromatography (IC) | Separates and quantifies sulfate ions using anion-exchange column and conductivity detection. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determines acidity/basicity of a 1% w/v aqueous solution using calibrated pH electrode. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles against defined standards under controlled lighting. |
| Melting Point | Capillary Melting Point Determination | Measures temperature range at which solid transitions to liquid using calibrated melting point apparatus. |
| Loss on Drying (LOD) | Gravimetric Analysis (Thermogravimetry) | Determines volatile matter loss by measuring weight change after drying at specified temperature and time. |
| Microbial Limits | Membrane Filtration and Plate Count | Evaluates total aerobic microbial count and absence of specified pathogens using filtration and agar culture. |
Technical Specifications of 161357-89-7
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 161357-89-7
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 161357-89-7
Packaging of 161357-89-7
Industrial 161357-89-7 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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