4-Cyanoindole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16136-52-0 |
| Product name | 4-Cyanoindole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Cyanoindole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Cyanoindole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Cyanoindole
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for sumatriptan and related anti-migraine agents | Serves as a key structural scaffold in constructing 5-HT1B/1D receptor agonist molecules via reduction, alkylation, and related reactions |
| Pharmaceuticals | Intermediate for indomethacin derivatives (non-steroidal anti-inflammatory drugs, NSAIDs) | Enables chemical modification of the indole ring system to introduce functional groups such as carboxylic acid for synthesizing anti-inflammatory drug molecules |
| Agrochemicals | Intermediate for plant growth regulators and indole-based fungicides | Facilitates synthesis of biologically active indole derivatives through functional group transformations on the indole ring |
| Organic Synthesis | Starting material for constructing indole-fused heterocyclic compounds | Participates in cyclization reactions via the C-4 cyano group to build fused-ring scaffolds such as indoloquinolones |
| Research Reagents | Structural modification and activity screening of indole compounds | Used for derivatization studies at the C-3, C-5, or N-1 positions of indole to explore bioactive molecules |
Manufacturing Quality Control of 4-Cyanoindole
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., indole, 4-aminoindole, isomeric cyanobenzenes) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., DMF, toluene, ethyl acetate) via gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol solvent system. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Determination of inorganic residue after controlled charring and high-temperature incineration (500–600 C), followed by weighing. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates or discoloration against established reference standards. |
| Loss on Drying | Thermogravimetric Analysis | Measurement of weight loss upon heating under controlled conditions (e.g., 105 C, 2 h) to determine volatile content. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of particle size distribution based on angular variation of laser light scattering intensity from dispersed sample. |
Technical Specifications of 4-Cyanoindole
| Test Item | Specification |
|---|---|
| Appearance | Brown solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 148–152°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Cyanoindole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Cyanoindole
Packaging of 4-Cyanoindole
Industrial 4-Cyanoindole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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