China Factory Direct
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| CAS number | 16136-58-6 |
| Product name | 1-Methylindole-2-carboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate | Used in the synthesis of biologically active indole derivatives as intermediates for drug molecule construction |
| Fine chemicals | Synthesis of specialty chemicals | Participates in coupling, esterification, and amidation reactions to produce functional organic molecules |
| Materials science | Functional materials research | Serves as a structural building block in research toward novel organic functional materials |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at ~254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV/DAD | Detects and quantifies structurally related impurities (e.g., 1-methylindole, indole-2-carboxylic acid) using gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Measures residual solvents (e.g., DMF, toluene, methanol) by headspace gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Determines total content of toxic elements (Pb, Cd, Hg, As) via inductively coupled plasma mass spectrometry after acid digestion. |
| Water Content | Karl Fischer Titration | Quantifies trace water by coulometric or volumetric titration using iodine-based redox reaction in anhydrous medium. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated capillary apparatus per USP <741>. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled high-temperature ashing (700–800 °C) and weighing. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Optical Rotation | Polarimetry | Measures specific rotation using sodium D-line light to assess chiral purity (if applicable; compound is achiral but method verifies absence of chiral contaminants). |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determines pH of a standardized suspension (e.g., 1% w/v in water) using calibrated pH electrode to assess acidic/basic impurity load. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry powder particle size distribution via Mie scattering theory using automated laser diffraction instrument. |
| Microbial Contamination | Membrane Filtration & Plate Count | Detects aerobic microorganisms per Ph. Eur. 2.6.12 using membrane filtration followed by incubation on TSA agar. |
| Appearance (Color & Clarity) | Visual Inspection & Hazen Color Scale | Assesses visual clarity and color intensity (in solution) against platinum-cobalt standards per USP <631>. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.