(R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 161511-90-6 |
| Product name | (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Synthesis of pharmaceutical intermediates for bioactive organic compounds | Used as a key intermediate in organic synthesis—e.g., nucleophilic substitution, cyclization—to incorporate the (R)-1-BOC-2-azetidinemethanol scaffold into target molecules |
| Chemical Research | Chiral reagent or intermediate for asymmetric synthesis studies | Applied in asymmetric catalytic reactions leveraging its chiral center to construct complex chiral molecules |
| Organic Synthesis | Synthesis of nitrogen-containing heterocycles, such as azetidine derivatives | Converted into functionalized compounds via deprotection and functional group transformations |
Manufacturing Quality Control of (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Chiral Purity (Enantiomeric Excess) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection; enantiomeric excess calculated from peak area ratio. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., THF, ethyl acetate, heptane) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion, with detection limits <1 ppb. |
| Residual BOC Reagent (Di-tert-butyl dicarbonate) | GC-MS | Gas chromatographic separation followed by mass spectrometric detection for specific identification and quantification of unreacted Boc₂O. |
| Related Substances | HPLC-UV (Forced Degradation Compatible) | Gradient HPLC-UV method validated for detection and quantification of process-related impurities and degradation products (e.g., de-Boc analog, ring-opened species). |
| Appearance & Color | Visual Inspection / APHA Color Scale | Subjective assessment of physical state (white to off-white crystalline solid) and quantitative color measurement against platinum-cobalt standards. |
| Melting Point | DSC or Capillary Melting Point Apparatus | Thermal transition analysis detecting sharp endothermic peak corresponding to crystalline melting behavior; typical range: 72–76 °C. |
| Residue on Ignition | Gravimetric Analysis | High-temperature ashing (700–800 °C) followed by weighing of inorganic residue to assess inorganic impurity load. |
| pH (1% w/v aqueous suspension) | pH Meter | Measurement of aqueous suspension pH to detect acidic/basic degradation products or residual catalysts (e.g., HCl, NaOH). |
Technical Specifications of (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +15.0 to +17.0 deg (c=1, in CHCl3) |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL
Safety Information of (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL
Industrial (R)-1-(TERT-BUTOXYCARBONYL)-2-AZETIDINEMETHANOL Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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