BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16159-70-9 |
| Product name | BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Reagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Chiral intermediate for D-phenylalanine protection in chiral drug synthesis, used in the preparation of protease inhibitors, antiviral agents, and other therapeutics | Used as an N-terminal protecting amino acid derivative in solid-phase peptide synthesis; the BOC group provides acid-labile protection, while the 4-nitrophenyl ester activates the carboxyl group for coupling reactions |
| Organic Synthesis | Chiral auxiliary or substrate in asymmetric catalysis and chiral resolution | Undergoes amidation with amines under basic conditions, or is hydrolyzed or aminolyzed to prepare other D-phenylalanine derivatives |
| Research | Studying structure–activity relationships and enzyme recognition mechanisms of D-amino acids in biological systems | Serves as a model substrate for stereoselectivity studies of proteolytic enzymes (e.g., trypsin, chymotrypsin) |
Manufacturing Quality Control of BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., BOC-D-Phe, nitrophenol, hydrolysis products) via gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DCM, DMF, toluene) using flame ionization detection after headspace or direct injection. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration based on iodine-sulfur dioxide reaction in pyridine/methanol medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-OES | Quantifies metal impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion by plasma emission spectroscopy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing at 700-800 C. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using controlled heating and visual observation. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of foreign particles under controlled white light against standard references. |
| pH of Solution | pH Meter | Measures hydrogen ion activity in a standardized suspension (e.g., 1% w/v in water/IPA mixture) using calibrated electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine size distribution based on light scattering pattern analysis. |
Technical Specifications of BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 82–86°C |
| Optical Rotation | -28° to -32° (c=1, in DMF) |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER
Packaging of BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER
Industrial BOC-D-PHENYLALANINE 4-NITROPHENYL ESTER Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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