(S)-(+)-Glycidyl Phthalimide Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 161596-47-0 |
| Product name | (S)-(+)-Glycidyl Phthalimide |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-(+)-Glycidyl Phthalimide
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-(+)-Glycidyl Phthalimide Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-(+)-Glycidyl Phthalimide
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthetic intermediate for preparing β-blockers (e.g., (S)-propranolol), antiviral agents, and other chiral drug molecules | Used as an epoxide and phthalimide-protected amino source to introduce chiral centers in asymmetric synthesis; commonly employed in nucleophilic ring-opening reactions to construct C–N or C–O bonds |
| Agrochemicals | Synthesis of chiral agrochemical intermediates | Applied to construct optically active agrochemical molecular scaffolds, enhancing biological activity and selectivity |
| Fine Chemicals | Chiral auxiliary or building block | Participates in multi-step organic synthesis; its epoxide moiety undergoes regio- and stereoselective ring opening, followed by phthalimide deprotection to yield chiral amino alcohol structures |
Manufacturing Quality Control of (S)-(+)-Glycidyl Phthalimide
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample under natural light or standard illumination to determine whether it is a white to off-white crystalline powder and to check for visible impurities. |
| Purity (Active Ingredient Content) | High-Performance Liquid Chromatography (HPLC) | Utilize reversed-phase HPLC (e.g., C18 column) with an appropriate mixture of water and organic solvent (e.g., acetonitrile/methanol) as the mobile phase, and detect using a UV detector (typically at 220–254 nm). Quantify the main peak content using the external standard method or area normalization method. |
| Enantiomeric Purity (ee value) | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use a chiral stationary phase column (e.g., Chiralpak AD-H, OD-H, etc.) under normal-phase conditions (e.g., n-hexane-isopropanol) to separate enantiomers, determine the ratio of (S)- and (R)-isomers, and calculate enantiomeric excess (ee). |
| Residual Solvents | Gas Chromatography (GC) | According to ICH Q3C guidelines, use headspace sampling-GC to detect organic solvents used during production (e.g., methanol, ethanol, acetone, dichloromethane), with FID detector for quantification. |
| Water Content | Karl Fischer Titration | Determine water content in the sample using volumetric or coulometric methods, suitable for precise control of low moisture levels. |
| Melting Point | Melting Point Instrument Method | Measure the initial and final melting temperatures of the compound using an automatic or capillary melting point apparatus for identification and preliminary purity assessment. |
| Infrared Spectroscopy (IR) | Fourier Transform Infrared Spectroscopy (FT-IR) | Obtain the infrared absorption spectrum by pressing the sample with potassium bromide or using ATR technique, and compare with a reference spectrum to confirm characteristic functional groups. |
| Nuclear Magnetic Resonance (NMR) | ¹H NMR and ¹³C NMR | Dissolve the sample in a deuterated solvent (e.g., DMSO-d6) and analyze the NMR spectra to verify molecular structure and stereochemistry, aiding in identification and purity assessment. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Sulfide Method (Pharmacopoeia Method) | Detect residual harmful elements such as lead, arsenic, and mercury. ICP-MS offers high sensitivity for trace metal analysis; traditional methods may follow the Chinese Pharmacopoeia or USP general chapters. |
| Residue on Ignition | Gravimetric Method (Sulfated Ash) | Ignite the sample at high temperature, treat with sulfuric acid, and weigh the residual ash to evaluate the content of inorganic impurities. |
Technical Specifications of (S)-(+)-Glycidyl Phthalimide
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Optical Rotation | +7.0 to +13.0 deg (c=1, in CHCl3) |
| Melting Point | 128 to 132 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-(+)-Glycidyl Phthalimide
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-(+)-Glycidyl Phthalimide
Packaging of (S)-(+)-Glycidyl Phthalimide
Industrial (S)-(+)-Glycidyl Phthalimide Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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