2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 161599-46-8 |
| Product name | 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Anticancer drug intermediate | Used in the synthesis of fluorouracil-based antimetabolite anticancer agents; applied to structural modification and prodrug optimization studies of capecitabine. |
| Pharmaceutical R&D | Key building block for nucleoside analog synthesis | Applied as a 5′-deoxy, 2′/3′-hydroxyl-protected fluorocytidine derivative in solid-phase or solution-phase nucleoside synthesis to construct novel antiviral or anticancer nucleotide analogs. |
Manufacturing Quality Control of 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identity | Infrared Spectroscopy (IR) | Confirms compound structure through characteristic functional group absorption peaks (e.g., C=O, C–F, N–H). |
| Proton Nuclear Magnetic Resonance (¹H NMR) | Analyzes chemical shifts, coupling constants, and integration ratios of hydrogen atoms to verify molecular structure and substitution patterns. | |
| Mass Spectrometry (MS) | Determines molecular ion peaks ([M+H]⁺ or [M+Na]⁺, etc.) to confirm molecular weight and characteristic fragment ions. | |
| Assay | High-Performance Liquid Chromatography with UV detection (HPLC-UV) | Uses a reversed-phase C18 column and UV detector (typically at 260–280 nm); quantifies the main component using external standard or area normalization method. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography with UV detection (HPLC-UV) | Uses same conditions as assay or gradient elution to separate and quantify potential impurities (e.g., starting materials, intermediates, degradation products). |
| Residual Solvents | Gas Chromatography with Flame Ionization or Mass Spectrometric Detection (GC-FID or GC-MS) | Headspace or direct injection used to detect organic solvents possibly remaining from synthesis or purification (e.g., ethyl acetate, dichloromethane). |
| Water Content | Karl Fischer Titration | Volumetric or coulometric method to determine water content in sample, ensuring compliance with loss on drying requirements. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Constant Temperature Drying Method | Sample dried under vacuum at specified temperature (e.g., 60–80°C) to constant weight to measure total volatile content. |
| Melting Point | Melting Point Apparatus | Determines the melting temperature range of the compound, serving as a physical constant for identification and purity assessment. |
| Specific Optical Rotation | Polarimeter | Solution of defined concentration is prepared; optical rotation measured at specified wavelength (usually sodium D line, 589 nm) to verify optical purity. |
| Elemental Analysis (Optional) | Elemental Analyzer (CHNS/O) | Measures weight percentages of elements such as C, H, N, and S; compares results with theoretical values to confirm compound composition. |
Technical Specifications of 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | -15.0° to -19.0° (c=1, in methanol) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
Safety Information of 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
| Pictograms |    |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine
Industrial 2',3'-Di-O-acetyl-5'-deoxy-5-fuluro-D-cytidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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