1-N-Cbz-4-cyanopiperidine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 161609-84-3 |
| Product name | 1-N-Cbz-4-cyanopiperidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 1-N-Cbz-4-cyanopiperidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1-N-Cbz-4-cyanopiperidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1-N-Cbz-4-cyanopiperidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a key intermediate in synthesizing piperidine-containing drug molecules, including analgesics, antidepressants, and NK1 receptor antagonists | In organic synthesis, the piperidine nitrogen is protected with Cbz (benzyloxycarbonyl); the cyano group is further converted to functional groups such as amides, tetrazoles, or carboxylic acids, enabling participation in multistep syntheses |
| Agricultural Chemicals | Used to construct nitrogen-containing heterocyclic scaffolds with biological activity | Applied as a structural building block in pesticide molecule design; specific substituents are introduced via cyano group transformations to optimize biological activity |
| Chemical Research | Used to develop novel piperidine derivatives and investigate the reactivity of cyano-substituted heterocyclic compounds | Employed as a standard building block in laboratory-scale synthetic methodology studies, including Suzuki coupling, reductive cyclization, and nucleophilic addition |
Manufacturing Quality Control of 1-N-Cbz-4-cyanopiperidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 220 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities by gradient HPLC-UV, using relative response factors or external standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., ethyl acetate, methanol) via headspace GC with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generated electrochemically in pyridine-free reagent. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (Pb, Cd, Hg, As, etc.) after acid digestion, using mass spectrometry for multi-element detection at sub-ppt levels. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled ashing at 600-700 C and weighing of the cooled crucible. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant eutectic impurities. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine volume-based particle size distribution (D10, D50, D90). |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension (e.g., 10% w/v in water) using calibrated pH electrode. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtering sample solution, culturing on soybean-casein digest agar, and counting colony-forming units. |
Technical Specifications of 1-N-Cbz-4-cyanopiperidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Melting Point | 45–49°C |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 1-N-Cbz-4-cyanopiperidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1-N-Cbz-4-cyanopiperidine
Packaging of 1-N-Cbz-4-cyanopiperidine
Industrial 1-N-Cbz-4-cyanopiperidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply