4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 161622-14-6 |
| Product name | 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of anticancer drugs, kinase inhibitors (e.g., BTK inhibitor analogs), and other active pharmaceutical ingredients (APIs) | Used as a bifunctional aryl bromide–trifluoromethyl building block in Suzuki couplings, Heck reactions, or amidation to construct core structures of targeted molecules |
| Pesticide R&D | Structural optimization intermediate for novel insecticides and herbicides | Applied to introduce a strongly electron-withdrawing trifluoromethyl group and a derivatizable bromine atom, enhancing compound lipophilicity, metabolic stability, and target-binding affinity |
| Materials Science | Precursor for electron-transport layer functional materials in organic light-emitting diode (OLED) devices | Modified via esterification or amidation to prepare trifluoromethyl-substituted benzoic acid derivatives, enabling tuning of HOMO/LUMO energy levels and thin-film morphology |
Manufacturing Quality Control of 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, toluene) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via electrochemical endpoint detection. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and others after acid digestion, using plasma excitation and optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against NaCl calibration curve. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by sulfuric acid treatment and final weighing of non-volatile residue. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and homogeneity against defined reference standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measurement of particle size distribution in dry or wet dispersion using Mie scattering theory and optical detection. |
| Acid Value | Acid-Base Titration | Neutralization of carboxylic acid groups with standardized NaOH solution using phenolphthalein indicator or potentiometric endpoint. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light source to detect chiral impurities or enantiomeric excess. |
Technical Specifications of 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID
Safety Information of 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID
Industrial 4-BROMO-3-(TRIFLUOROMETHYL)BENZOIC ACID Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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