China Factory Direct
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| CAS number | 161879-12-5 |
| Product name | H-PHG-OTBU HCL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Organic synthesis intermediate for constructing piperidine-containing drug molecules | Used as a chiral building block in coupling, substitution, or reductive amination reactions to synthesize small-molecule candidate drugs targeting G protein-coupled receptors (GPCRs) |
| Fine Chemicals | Chiral catalyst ligand precursor | Derivatized to prepare chiral phosphine–nitrogen hybrid ligands for asymmetric hydrogenation or C–C bond formation reactions |
| Detection Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe sample color, form, crystalline state, etc., to ensure compliance with specified standards (e.g., white to off-white crystalline powder). |
| Identification | Infrared Spectroscopy (IR) | Compare infrared absorption spectrum with that of reference standard to confirm consistency of molecular structural characteristic peaks. |
| High-Performance Liquid Chromatography (HPLC) | Confirm identity of the main component based on matching retention time with reference substance. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Determine content of the main component using external standard or internal standard method by calculating peak area; typically requires ≥98.0% to 102.0%. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) | Separate impurities using gradient or isocratic elution; calculate total impurity level and individual impurity limits by area normalization or main component self-control method. |
| Loss on Drying | Drying Method (105°C, constant weight) | Dry weighed sample in an oven until constant weight, calculate percentage of mass loss to assess moisture and volatile content. |
| Residue on Ignition | Furnace Incineration Method (600–800°C) | After charring, incinerate sample at high temperature; weigh residual inorganic matter to assess inorganic impurity levels (typically ≤0.1%). |
| Heavy Metals | Silver Thioglycollate Method (as per Chinese Pharmacopoeia) | React with thioglycollate under weakly acidic conditions to produce visible coloration; compare with standard lead solution to control total heavy metal content (e.g., ≤20 ppm). |
| pH Value | pH Meter Measurement | Prepare a solution of specified concentration (e.g., 1%), then measure pH using a calibrated pH meter to ensure it falls within the required range (e.g., 4.0–6.0). |
| Residual Solvents | Gas Chromatography (GC), Headspace Injection | Detect possible residual organic solvents (e.g., methanol, ethanol, ethyl acetate) from synthesis or purification processes according to ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Determine water content using either volumetric or coulometric Karl Fischer titration, especially suitable for thermally unstable or hygroscopic samples. |
| Specific Rotation | Polarimeter Measurement | Prepare a solution of specified concentration, measure optical rotation under specified wavelength (usually sodium D line) and temperature; used for quality control of chiral compounds. |
| Solution Clarity and Color | Visual Comparison / Turbidity Test | Compare prepared solution visually with standard color or turbidity reference solutions to evaluate clarity and detect any abnormal discoloration. |
| Test Item | Specification |
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| Appearance | White Solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 142-146°C |
| Optical Rotation | +35.0 to +37.0° (c=1, in 1M HCl) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.