4-Methylthiophenylacetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16188-55-9 |
| Product name | 4-Methylthiophenylacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methylthiophenylacetic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methylthiophenylacetic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methylthiophenylacetic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for certain antidepressants and psychotropic drugs | Produced via organic synthesis, including nucleophilic substitution and condensation reactions |
| Chemical Synthesis | Organic synthesis intermediate for preparing other sulfur-containing compounds | Prepared through chemical reaction processes such as methylation, esterification, and reduction |
| Pesticides | Intermediate in the synthesis of certain herbicides or insecticides | Manufactured by introducing sulfur functional groups followed by structural modification |
Manufacturing Quality Control of 4-Methylthiophenylacetic acid
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol/water or acetonitrile/buffer salt as the mobile phase, and UV detection (e.g., 220 nm or 254 nm) for quantitative analysis of main component purity. Suitable for accurately determining the content of 4-methylthiophenylacetic acid and impurity profile in samples. |
| Related Substances / Impurity Analysis | HPLC-UV or HPLC-DAD | Extends run time or employs gradient elution based on purity determination to separate and quantify potential process impurities and degradation products. DAD aids in peak purity assessment and preliminary structural screening of impurities. |
| Moisture Content | Karl Fischer Titration | Measures trace moisture using coulometric or volumetric Karl Fischer methods, suitable for controlling trace water in organic compounds, ensuring product stability and compliance with storage requirements. |
| Residual Solvents | Gas Chromatography (GC-FID or GC-MS) | Uses headspace or direct injection with capillary columns for separation, and FID detector for quantification of residual organic solvents (e.g., methanol, ethyl acetate, dichloromethane), compliant with ICH Q3C guidelines. |
| Melting Point Determination | Capillary Melting Point Apparatus Method | Determines the solid-to-liquid transition temperature during heating, indicating physical purity and crystalline state; a routine identification and quality control parameter for active pharmaceutical ingredients. |
| Structure Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | NMR (¹H, ¹³C) provides molecular framework and substitution information; IR confirms functional groups (e.g., carboxylic acid, aromatic ring, thioether); MS determines molecular weight and fragmentation patterns. Combined use confirms chemical structure. |
| Heavy Metal Residues | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After sample digestion, measures levels of lead, cadmium, arsenic, mercury, and other elemental impurities, meeting ICH Q3D requirements for element impurity control and ensuring safety. |
| Drying Loss | Drying Weight Loss Method | Dries sample at a specified temperature (e.g., 105°C) until constant weight, calculating the percentage loss due to volatile substances, indirectly reflecting moisture and easily volatile impurities. |
| pH Value (if in solution form) | pH Meter Measurement | Prepared as an aqueous solution at a defined concentration, measured using a calibrated pH meter to assess acidity/basicity, affecting solubility and formulation compatibility. |
| Specific Rotation (if chiral) | Polarimeter Measurement | If the molecule contains a chiral center, specific rotation must be determined to control enantiomeric purity—particularly critical in asymmetric synthesis processes. |
Technical Specifications of 4-Methylthiophenylacetic acid
| Test Item | Specification |
|---|---|
| Appearance | White to yellow to orange crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 124–128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methylthiophenylacetic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methylthiophenylacetic acid
Safety Information of 4-Methylthiophenylacetic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Methylthiophenylacetic acid
Industrial 4-Methylthiophenylacetic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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