China Factory Direct
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| CAS number | 161957-61-5 |
| Product name | 3'-Bromo-2'-Fluoroacetophenone |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate in the synthesis of antitumor agents (e.g., EGFR inhibitors) | Acetylation of bromofluorobenzene followed by amination and cyclization to construct the quinazoline scaffold |
| Agrochemical Intermediates | Used in the preparation of novel fluorinated insecticides and fungicides | Serves as a fluorinated aryl ketone building block in condensation reactions with hydrazides or amines |
| Organic Synthesis | Preparation of multifunctional fluoro-substituted aryl ketones | Introduction of additional aryl or alkenyl groups via transition-metal-catalyzed reactions such as Suzuki coupling and Heck reaction |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | GC-FID or HPLC-UV | Quantifies main component by comparing peak area against calibrated standard. |
| Related Substances | HPLC-DAD or UPLC-MS | Separates and detects impurities based on retention time and spectral/ mass characteristics. |
| Residual Solvents | GC-FID with headspace | Volatile solvents are extracted in headspace and quantified using calibrated standards. |
| Water Content | Karl Fischer Titration | Measures water via stoichiometric reaction between iodine, sulfur dioxide, and water in methanol/pyridine medium. |
| Heavy Metals (as Pb) | ICP-OES | Elemental quantification after acid digestion using plasma excitation and emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride anions using conductivity detection after ion exchange. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid under controlled heating. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light induced by chiral molecules in solution. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against standard reference under controlled lighting. |
| pH of Aqueous Solution | pH Meter | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated electrode. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution by analyzing angular variation in laser light scattering pattern. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Refractive Index (n20/D) | 1.570–1.575 |
| Relative Density (20°C/25°C) | 1.480–1.490 g/cm³ |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.