4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 162012-67-1 |
| Product name | 4-Quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitro- |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 162012-67-1
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 162012-67-1 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 162012-67-1
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a tyrosine kinase inhibitor in anticancer drug research | Chemical synthesis and biological activity screening |
| Biochemical Research | Employed as a molecular probe or inhibitor targeting the EGFR signaling pathway | In vitro cell-based assays and kinase activity assays |
| Drug Development | Served as a lead compound for structural optimization of novel anticancer agents | Structure–activity relationship (SAR) studies and molecular modification |
Manufacturing Quality Control of 162012-67-1
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at characteristic wavelength based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities by comparing retention times and peak areas to reference standards or threshold responses. |
| Residual Solvents | GC-FID | Measures volatile organic solvents using gas chromatography with flame ionization detection, calibrated against solvent standards. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration using iodine-based reagent where water reacts stoichiometrically with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Ni) via inductively coupled plasma mass spectrometry after acid digestion and matrix separation. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with conductivity detection, calibrated against sodium chloride standards. |
| Residual Palladium | ICP-OES | Measures palladium from catalytic hydrogenation residues using inductively coupled plasma optical emission spectroscopy after microwave digestion. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation of phase change. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution by analyzing angular variation in laser light scattering pattern from dispersed sample. |
| Bulk Density | USP <616> Tap Density Method | Determines mass per unit volume of powder after standardized tapping; calculated from weight and tapped volume. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms by filtering sample through membrane, then culturing on soybean-casein digest agar under controlled conditions. |
| Optical Rotation | Polarimetry | Measures specific rotation using plane-polarized light passing through solution; indicates chiral purity and enantiomeric excess. |
Technical Specifications of 162012-67-1
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.5% (LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–219°C |
| Identification (NMR) | Conforms to reference standard |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 162012-67-1
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 162012-67-1
Packaging of 162012-67-1
Industrial 162012-67-1 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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