5-Pyrazolecarboxylic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1621-91-6 |
| Product name | 5-Pyrazolecarboxylic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Pyrazolecarboxylic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Pyrazolecarboxylic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Pyrazolecarboxylic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate in the synthesis of celecoxib and other coxibs (non-steroidal anti-inflammatory drugs) | Condensation with aromatic sulfonamides via acid chloride formation and amidation, using pyrazole-3-carboxylic acid as the starting material |
| Pharmaceutical Industry | Starting material for synthesizing urea-, amide-, or ester-based derivatives of compound F | Construction of drug molecular scaffolds via amidation with substituted amines or esterification with alcohols |
| Agrochemical Industry | Intermediate in the synthesis of insecticides, fungicides, and plant growth regulators | Modification and functionalization of pyrazole ring derivatives to produce biologically active agrochemical molecules |
| Dye Industry | Synthetic intermediate for functional dyes and organic pigments | Serving as either a diazo component or a coupling component in azo dye synthesis |
| Organic Synthesis | Raw material for ligand or catalyst ligand synthesis | Coordination or functionalization of the carboxyl group with central metal ions to prepare metal–organic frameworks or catalysts |
Manufacturing Quality Control of 5-Pyrazolecarboxylic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV against qualified reference standards or threshold-based reporting. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., methanol, acetone, ethyl acetate) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine generated electrochemically to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Quantitative determination of trace metals (e.g., Pb, Cd, Hg, As) after acid digestion, using mass spectrometry for elemental detection. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Ignition of sample at 700-800 C followed by weighing of residual inorganic ash after treatment with sulfuric acid. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature using controlled heating and visual observation of meniscus collapse. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled white light against established reference standards. |
| Loss on Drying | Thermogravimetric Analysis | Measurement of mass loss upon heating at 105 C for 2 hours, indicating volatile content including moisture and residual solvents. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, indicating chiral purity if applicable. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a saturated aqueous suspension using a calibrated glass electrode pH meter. |
Technical Specifications of 5-Pyrazolecarboxylic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 178–182°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Pyrazolecarboxylic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Pyrazolecarboxylic acid
Packaging of 5-Pyrazolecarboxylic acid
Industrial 5-Pyrazolecarboxylic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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