2,6-Difluorophenylboronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 162101-25-9 |
| Product name | 2,6-Difluorophenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,6-Difluorophenylboronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,6-Difluorophenylboronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,6-Difluorophenylboronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing anticancer agents, including tyrosine kinase inhibitors such as erlotinib and gefitinib | Constructs drug molecules containing a difluorophenyl scaffold via Suzuki–Miyaura coupling |
| Pharmaceuticals | Used in synthesizing neuroactive and anti-infective drugs | Introduces the 2,6-difluorophenyl group as an electrophilic or coupling reagent |
| Organic Synthesis | Used to construct fluorinated biaryl compounds | Serves as a boronic acid reagent in Suzuki coupling reactions |
| Liquid Crystal Materials | Used to synthesize high-performance liquid crystal monomers | Introduces rigid fluorinated phenyl ring structures via coupling reactions to enhance the physicochemical properties of liquid crystal molecules |
Manufacturing Quality Control of 2,6-Difluorophenylboronic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., residual aryl halides, boronic esters, phenols) relative to main peak using gradient HPLC-UV. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., THF, toluene, methanol) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generation in pyridine-free reagent; measures water via stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element detection after acid digestion; quantifies total heavy metals by atomic emission intensity at characteristic wavelengths. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of Pd catalyst residues following microwave-assisted acid digestion and isotopic mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on anion-exchange column with suppressed conductivity detection. |
| Sulfate Impurity | Ion Chromatography | Separation of sulfate anions on anion-exchange column with suppressed conductivity detection. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change in capillary tube under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under standardized white light and against white background. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying sample at specified temperature (e.g., 105 C) under vacuum or nitrogen until constant weight. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
Technical Specifications of 2,6-Difluorophenylboronic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 132-136°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,6-Difluorophenylboronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,6-Difluorophenylboronic acid
Safety Information of 2,6-Difluorophenylboronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 2,6-Difluorophenylboronic acid
Industrial 2,6-Difluorophenylboronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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