China Factory Direct
|
|
| CAS number | 1625-72-5 |
| Product name | S-Cbz-L-cysteine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for peptide synthesis; introduces the S-benzyloxycarbonyl (S-Z) protecting group to shield the thiol group of cysteine | Attached to the peptide chain via coupling reactions in solid-phase or solution-phase peptide synthesis; the protecting group is subsequently removed by hydrogenolysis |
| Biochemistry | Used in structural studies or modification of proteins/peptides as a protected form of cysteine | Chemically conjugated to target molecules under laboratory conditions to protect or derivatize specific functional groups |
| Pharmaceutical R&D | Raw material or intermediate for synthesizing active peptide drugs containing cysteine residues | Serves as a building block in drug synthesis processes, participating in synthetic routes via stepwise coupling or fragment assembly |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reversed-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase, with UV detection to determine enantiomeric excess. |
| Loss on Drying | Gravimetric (105 C oven drying) | Mass loss measured after drying sample at 105 C to constant weight, indicating volatile content including residual solvents and water. |
| Residual Solvents | GC-FID | Quantitative analysis of common organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element detection of heavy metals (Pb, Cd, Hg, As) by inductively coupled plasma optical emission spectrometry after acid digestion. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode to determine chloride ion concentration based on precipitation endpoint. |
| Sulfated Ash | Gravimetric (500-600 C) | Residue mass after incineration at 500-600 C following sulfuric acid treatment, indicating inorganic impurities. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 20 C using sodium D-line (589 nm) to confirm chiral integrity and concentration. |
| Water Content | Karl Fischer Titration | Coulometric or volumetric titration with KF reagent to quantify trace water based on iodine-sulfur dioxide reaction stoichiometry. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., de-Cbz product, disulfide dimer) using gradient HPLC-UV. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | pH determination of a 1% w/v aqueous solution using calibrated pH meter with glass electrode. |
| Microbial Limits | Membrane Filtration / TSA/SDA | Enumeration of aerobic bacteria, yeasts, and molds by membrane filtration followed by incubation on Tryptic Soy Agar and Sabouraud Dextrose Agar. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 138-142°C |
| Optical Rotation | -27° to -31° (c=1, 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.