FMOC-D-TYR(ET)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 162502-65-0 |
| Product name | FMOC-D-TYR(ET)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-D-TYR(ET)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-D-TYR(ET)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-D-TYR(ET)-OH
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Tyrosine protecting reagent in solid-phase peptide synthesis (SPPS) | Acts as a dual protecting group for the α-amino and phenolic hydroxyl groups of D-tyrosine: the Fmoc group protects the α-amino group, while the O-ethyl group protects the phenolic hydroxyl group; used to synthesize therapeutic peptides or structural probes containing D-tyrosine residues. The Fmoc group is selectively removed under piperidine/DMF conditions, leaving the O-ethyl group intact; final cleavage from the resin and simultaneous removal of the O-ethyl protecting group are achieved using strong acid (e.g., TFA) |
| Pharmaceutical R&D | Structural modification and structure–activity relationship (SAR) studies of chiral peptide candidates | Introduces configurationally stable D-tyrosine units to enhance peptide resistance to proteolytic degradation and improve target-binding specificity; suitable for combinatorial library construction and high-throughput screening |
| Chemical Biology | Intermediate for fluorescently labeled peptide probes | The fluorenyl moiety provides inherent UV absorbance, facilitating HPLC monitoring of coupling reactions; subsequent derivatization (e.g., conjugation with fluorescent dyes) yields active probes targeting tyrosine kinase signaling pathways |
Manufacturing Quality Control of FMOC-D-TYR(ET)-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorption at specific wavelength using reverse-phase chromatography with calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities via gradient reverse-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents using gas chromatography with flame ionization detection and internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water by coulometric or volumetric titration with iodine generated electrochemically in pyridine-methanol medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Quantifies trace metal contaminants (e.g., Pb, Cd, Ni) via inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Chloride | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Loss on Drying | Gravimetric Analysis | Determines volatile content by measuring weight loss after controlled heating under specified temperature and vacuum conditions. |
| pH of Aqueous Suspension | Potentiometric Titration | Measures hydrogen ion activity in saturated aqueous suspension using calibrated pH electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes size distribution by measuring angular variation in laser light scattering from dispersed particles. |
| Residual Fmoc Protecting Group | HPLC-UV | Quantifies unreacted or cleaved Fmoc moiety using reverse-phase HPLC with UV detection at 265 nm. |
| Microbial Limits | Membrane Filtration | Detects aerobic microorganisms by filtration, membrane transfer to culture media, and colony enumeration after incubation. |
Technical Specifications of FMOC-D-TYR(ET)-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Optical Rotation | +22 to +26° (c=1, DMF) |
| Melting Point | 148 to 152°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-D-TYR(ET)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-D-TYR(ET)-OH
Packaging of FMOC-D-TYR(ET)-OH
Industrial FMOC-D-TYR(ET)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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