3-Chlorophenylglycolic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16273-37-3 |
| Product name | 3-Chlorophenylglycolic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3-Chlorophenylglycolic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Chlorophenylglycolic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Chlorophenylglycolic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key chiral intermediate for the synthesis of the anti-thrombotic drug clopidogrel | Optically pure (S)-m-chloromandelic acid is prepared via asymmetric synthesis or chiral resolution, followed by multi-step reactions to construct the clopidogrel molecular scaffold |
| Pharmaceuticals | Synthesis of other cardiovascular drugs and biologically active chiral compounds | Used as a chiral building block in organic synthesis reactions such as condensation, esterification, and reduction |
| Fine Chemicals | Chiral auxiliary or chiral source | Provides stereochemical control in asymmetric catalysis or chirally induced reactions |
Manufacturing Quality Control of 3-Chlorophenylglycolic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and threshold limits per ICH Q3A. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other regulated metals after acid digestion, using isotopic detection for high sensitivity. |
| Chloride Content | Potentiometric Titration | Direct titration with silver nitrate using a silver indicator electrode; endpoint determined by potential inflection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric determination of water based on iodine-sulfur dioxide redox reaction in pyridine-methanol medium. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating; reported as onset and clear point per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 20 deg C using sodium D-line (589 nm); indicates enantiomeric purity. |
| Residue on Ignition | Gravimetric Analysis | Weighing of inorganic residue remaining after charring and incineration at 700-800 deg C for 1 hour. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a 1% w/v suspension in purified water using calibrated pH electrode per USP <791>. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity to determine volume-based particle size distribution in dispersed dry or wet sample. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and non-targeted screening of genotoxic and residual solvents using mass spectral library matching and quantification against internal standards. |
Technical Specifications of 3-Chlorophenylglycolic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Melting Point | 124-128°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Optical Rotation | -15° to -25° (c=1, in methanol) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3-Chlorophenylglycolic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Chlorophenylglycolic acid
Packaging of 3-Chlorophenylglycolic acid
Industrial 3-Chlorophenylglycolic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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