tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1628047-84-6 |
| Product name | tert-butyl 2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-bromobenzoate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 1628047-84-6
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 1628047-84-6 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 1628047-84-6
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Active Pharmaceutical Ingredients (APIs) and Pharmaceutical Intermediates | Serves as a key synthetic building block for targeted anticancer drugs such as Vismodegib, enabling construction and structural modification of drug molecules. |
| Pharmaceutical Industry | Drug Discovery | Applied in kinase inhibitor development, leveraging its pyrrolopyridine and bromobenzoate ester functionalities to perform Suzuki coupling and other reactions for screening biologically active compounds. |
| Chemical Industry | Organic Synthesis | Used in palladium-catalyzed cross-coupling reactions to introduce additional functional groups via the reactive bromine site, facilitating assembly of complex organic molecular frameworks. |
Manufacturing Quality Control of 1628047-84-6
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Heavy Metals | ICP-MS | Quantitative determination of trace metal elements (e.g., Pb, Cd, Hg, Ni) after acid digestion, using mass spectrometric detection. |
| Residual Palladium | ICP-MS | Specific quantification of palladium residue from catalytic synthesis steps via acid digestion and isotopic mass detection. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions after aqueous extraction and filtration. |
| Sulfate Impurity | Ion Chromatography | Separation and conductivity detection of sulfate ions following sample dissolution and matrix removal. |
| Residual t-Butyl Alcohol | GC-FID | Direct injection or headspace GC-FID analysis to quantify residual t-butyl alcohol from incomplete esterification or cleavage. |
| Optical Rotation | [a]D Measurement | Measurement of specific rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity (if applicable). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition detection via controlled heating of a capillary-packed sample until complete solid-to-liquid phase change. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using light scattering principles to determine volumetric particle size distribution. |
Technical Specifications of 1628047-84-6
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=99.0% (by LC-MS) |
| Total Impurities | <=1.0% (by LC-MS) |
| Single Impurity | <=0.5% (by LC-MS) |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 1628047-84-6
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 1628047-84-6
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Industrial 1628047-84-6 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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