2-AMINO-5-BROMOBENZAMIDE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16313-66-9 |
| Product name | 2-AMINO-5-BROMOBENZAMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-AMINO-5-BROMOBENZAMIDE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-AMINO-5-BROMOBENZAMIDE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-AMINO-5-BROMOBENZAMIDE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antitumor agents (e.g., BRAF inhibitors) | Prepared via multi-step organic synthesis, including amidation, nitration, reduction, or direct bromination–amination, starting from bromobenzoic acid derivatives |
| Agrochemicals | Structural building block for novel insecticides and fungicides | Introduced as a substituent into heterocyclic agrochemical molecules (e.g., benzimidazole derivatives) and participates in cyclization or coupling reactions |
| Materials Science | Used in the synthesis of high-performance fluorescent dyes and organic optoelectronic materials (e.g., hole-transport layers for OLEDs) | Integrated into conjugated backbones via Suzuki or Heck coupling, or condensed with aldehydes to construct Schiff base-type functional materials |
Manufacturing Quality Control of 2-AMINO-5-BROMOBENZAMIDE
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Characteristics | Visual Inspection, Microscopic Observation | Observe color, crystal form, caking, or presence of impurities. Should appear as a white to off-white crystalline powder with no visible foreign matter. |
| Melting Point | Capillary Melting Point Method (GB/T 617) | Determine the melting temperature range under standard conditions. Typically between 165–172°C, used for preliminary purity assessment. |
| Content Determination (Active Pharmaceutical Ingredient) | High-Performance Liquid Chromatography (HPLC) | Use C18 column, gradient elution with water-acetonitrile, UV detection at 254 nm, external standard method for quantification. Ensure API purity ≥98.0%. |
| Related Substances (Impurity Profile) | HPLC Method (Impurity Testing) | Same HPLC system; reduce detection wavelength (e.g., 220 nm) and extend gradient time to separate and quantify known/unknown impurities such as unreacted raw materials, debromination products, oxidation by-products. Total impurities ≤2.0%. |
| Bromine Content Determination | Combustion-Ion Chromatography or Oxygen Bomb Combustion + Bromide Selective Electrode | Completely combust sample and absorb bromide ions (Br⁻) in alkaline solution. Quantify Br⁻ using ion chromatography or bromide-selective electrode. Verify bromine content matches theoretical value (theoretical Br ≈ 37.5%). |
| Water Content | Karl Fischer Titration (KF Method) | Determine trace moisture using coulometric or volumetric KF titration. Control water content ≤0.5% to prevent hydrolysis or stability issues during storage. |
| Solvent Residues | Gas Chromatography (GC) | Use DB-624 or HP-INNOWAX column with headspace injection. Detect residual organic solvents (e.g., methanol, ethanol, ethyl acetate, DMF), complying with ICH Q3C guidelines. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After acid digestion, determine levels of lead, cadmium, mercury, arsenic, etc. Limit: ≤10 ppm, meeting pharmaceutical-grade requirements. |
| pH Value (Aqueous Solution) | pH Meter Method | Dissolve sample in water to prepare a 1% solution, then measure pH. Typically neutral (pH 5.5–7.5), reflecting acidity/alkalinity impurities. |
| Particle Size Distribution (if applicable) | Laser Diffraction or Microscopic Sieving Method | For raw materials intended for formulation, determine particle size distribution to ensure flowability and dissolution properties meet process requirements. |
| UV-Visible Absorption Spectrum | UV-Vis Spectrophotometry | Scan absorption spectrum in the range of 200–400 nm. Characteristic peak(s) at λmax ≈ 260–280 nm for structural confirmation and auxiliary purity evaluation. |
Technical Specifications of 2-AMINO-5-BROMOBENZAMIDE
| Test Item | Specification |
|---|---|
| Appearance | White to almost white crystalline powder |
| Purity | >=98.0% (LC-MS) |
| Melting Point | 172–176°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-AMINO-5-BROMOBENZAMIDE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-AMINO-5-BROMOBENZAMIDE
Packaging of 2-AMINO-5-BROMOBENZAMIDE
Industrial 2-AMINO-5-BROMOBENZAMIDE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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