China Factory Direct
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| CAS number | 163277-80-3 |
| Product name | AC-THR(TBU)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Pharmaceutical intermediates | Used as a key chiral intermediate in the synthesis of antiviral drugs (e.g., HIV protease inhibitors) |
| Pharmaceuticals | Chiral compound synthesis | Applied to construct active pharmaceutical ingredients (APIs) with defined stereochemistry |
| Chemical synthesis | Organic synthesis reagent | Employed as a chiral auxiliary or structural building block in asymmetric synthesis |
| R&D | New drug development | Utilized to explore synthetic routes for novel peptide- and peptidomimetic compounds |
| Biopharmaceuticals | Peptide synthesis | Applied to construct chiral-center-containing peptide fragments for biological activity studies |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | (S,S)- and (R,R)-Diastereomer Content | Chiral HPLC with polysaccharide-based column and UV detection; separates diastereomers based on stereospecific interactions. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation of sample solution at 20 C using sodium D-line (589 nm) to confirm enantiomeric identity and purity. |
| Residual Solvents | GC-FID | Quantifies volatile organic solvents (e.g., THF, EtOAc, MeOH) by gas chromatography with flame ionization detection against internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Measures trace metal impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Residual Chloride | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Related Substances | HPLC-UV (Forced Degradation Study) | Detects and quantifies structurally related impurities (e.g., deacetylated, hydrolyzed, or oxidized derivatives) under stressed conditions. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measures pH of 1% w/v suspension in water using calibrated pH electrode to assess acidic/basic impurity impact. |
| Particle Size Distribution | Laser Diffraction | Determines size distribution of solid particles in dry dispersion mode using Mie scattering theory and optical detection. |
| Loss on Drying | Gravimetric Thermogravimetry | Measures weight loss after drying at 60 C under vacuum for 2 hours to quantify volatile and moisture content. |
| Microbial Limits | Membrane Filtration and Plate Count | Detects aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112-116°C |
| Optical Rotation | +15.0 to +17.0° (c=1, in methanol) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.