4-Ethylbenzoyl chloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16331-45-6 |
| Product name | 4-Ethylbenzoyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Ethylbenzoyl chloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Ethylbenzoyl chloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Ethylbenzoyl chloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of pharmaceutical intermediates for antihypertensive, antifungal, and anti-inflammatory drugs | Used as an acylating agent to form amide bonds with amines |
| Agrochemicals | Key intermediate in the production of herbicides, fungicides, and other agrochemicals | Introduces the 4-ethylbenzoyl group via acid chloride formation to enhance biological activity |
| Dyes & Pigments | Synthesis of azo dyes and other high-performance pigments | Serves as a coupling component or modifying group to improve hue and stability |
| Polymer Materials | Preparation of polymer modifiers or functional monomers | Introduces aromatic acyl chloride groups via polymerization to enhance material properties |
| Organic Synthesis | General-purpose acylating agent for introducing the 4-ethylbenzoyl group | Acts as an acyl chloride donor in Friedel–Crafts acylation and related reactions |
Manufacturing Quality Control of 4-Ethylbenzoyl chloride
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Purity (Active Ingredient Content) | Gas Chromatography (GC) | Using a capillary chromatographic column and a hydrogen flame ionization detector (FID) for measurement. Quantification is performed using internal or external standard methods, effectively separating p-ethylbenzoyl chloride and its impurities (such as unreacted p-ethylbenzoic acid, dimers, etc.). |
| Water Content | Karl Fischer Titration | Utilizing Karl Fischer reagent composed of iodine, sulfur dioxide, pyridine, and methanol to quantitatively react with water. The endpoint is determined by potentiometric or amperometric methods, accurately measuring trace amounts of moisture suitable for moisture-sensitive acyl chloride compounds. |
| Chlorine Content | Oxygen Bomb Combustion - Ion Chromatography / Argentometric Titration | In the oxygen bomb combustion method, the sample is completely oxidized, and chlorine is converted into chloride ions for determination by ion chromatography; alternatively, argentometric titration (Fajans method) can be used, determining chloride content by precipitation endpoint to verify whether the chlorine atoms in the molecule meet the specifications. |
| Appearance and Color | Visual Inspection + Spectrophotometry | Observe whether the sample is a colorless to slightly yellow transparent liquid without suspended solids; if necessary, use a UV-Vis spectrophotometer in the visible range (e.g., 400–700 nm) to measure absorbance and evaluate whether the color meets the standard. |
| Acid Value (Free Acids) | Non-aqueous Titration | Dissolve the sample in a non-aqueous solvent (e.g., glacial acetic acid), titrate with perchloric acid standard solution, and determine the endpoint by potentiometric or indicator methods to measure free acidic impurities such as p-ethylbenzoic acid. |
| Melting Point / Boiling Point | Digital Melting Point Apparatus / Reduced Pressure Distillation | p-Ethylbenzoyl chloride is a liquid; its boiling point range is determined by reduced pressure distillation (approximately 210–220°C at atmospheric pressure, lower under vacuum), used to verify purity and volatility characteristics. |
| Impurity Profile (Organic Impurities) | High-Performance Liquid Chromatography (HPLC) | Using a C18 column and an acetonitrile/water or methanol/water mobile phase with a UV detector to separate and quantify polar or thermally unstable impurities, such as hydrolysis products and oxidation byproducts. |
| Stability (Hydrolysis Sensitivity) | Hydrolysis Followed by GC/HPLC Analysis | Analyze hydrolysis products (p-ethylbenzoic acid) after reacting the sample with a small amount of water using GC or HPLC to assess sensitivity to moisture, used for process control and packaging requirement evaluation. |
| Heavy Metal Content | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, use AAS or inductively coupled plasma mass spectrometry (ICP-MS) to determine heavy metal residues such as lead, cadmium, and mercury to ensure compliance with pharmaceutical or high-purity chemical standards (e.g., ICH Q3D). |
Technical Specifications of 4-Ethylbenzoyl chloride
| Test Item | Specification |
|---|---|
| Appearance | Light yellow liquid |
| Purity | >=98.5% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.532–1.536 |
| Relative Density (20°C/25°C) | 1.110–1.120 g/cm³ |
| Odor | Characteristic pungent acrid odor |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Ethylbenzoyl chloride
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| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Ethylbenzoyl chloride
Packaging of 4-Ethylbenzoyl chloride
Industrial 4-Ethylbenzoyl chloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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