(R)-Boc-Nipecotic acid Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 163438-09-3 |
| Product name | (R)-Boc-Nipecotic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for (R)-Boc-Nipecotic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-Boc-Nipecotic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-Boc-Nipecotic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug intermediates for synthesizing bioactive molecules (e.g., inhibitors, receptor antagonists) | Organic synthesis, chiral resolution, Boc protecting group introduction and deprotection |
| Chemical Research | Chiral building blocks for constructing complex organic molecules (e.g., natural products, functional materials) | Asymmetric synthesis, catalytic reactions, structural modification |
| Pharmaceutical R&D | Clinical trial compound or drug candidate preparation | Multistep synthesis, purification (chromatography, crystallization), analytical characterization |
Manufacturing Quality Control of (R)-Boc-Nipecotic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and enantiomeric excess calculation. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection, quantifying common solvents (e.g., methanol, ethyl acetate) against calibration standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water based on stoichiometric reaction with iodine and sulfur dioxide. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Ni) after acid digestion, using mass spectrometric detection. |
| Residual Palladium | ICP-OES | Quantification of palladium catalyst residue after microwave-assisted acid digestion, via atomic emission spectroscopy. |
| Acid Value | Acid-Base Titration | Neutralization of free carboxylic acid groups with standardized NaOH solution using phenolphthalein indicator. |
| Appearance | Visual Inspection | Comparison of sample color and clarity against water-white standard under controlled white light and specified viewing conditions. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change in a capillary tube under controlled heating rate. |
| Loss on Drying | Gravimetric Analysis | Mass loss measurement after drying under vacuum at 60 C for 2 hours, expressed as weight percent. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities using gradient HPLC with UV detection at multiple wavelengths. |
| Residual Boc Group | 1H NMR Spectroscopy | Qualitative and semi-quantitative assessment of tert-butoxycarbonyl group integrity via integration of characteristic t-butyl proton signals (1.4 ppm). |
Technical Specifications of (R)-Boc-Nipecotic acid
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC) |
| Optical Rotation | -53.0 to -49.0 deg (c=1, in CHCl3) |
| Total Impurities | <=2.0% (GC) |
| Single Impurity | <=0.5% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 78 to 82 °C |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of (R)-Boc-Nipecotic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-Boc-Nipecotic acid
Packaging of (R)-Boc-Nipecotic acid
Industrial (R)-Boc-Nipecotic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply