China Factory Direct
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| CAS number | 163439-82-5 |
| Product name | (3R,4R)-(-)-1-BENZYL-3,4-PYRROLIDINDIOL |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in drug synthesis | Employed in subsequent drug molecule construction following chiral resolution or asymmetric synthesis |
| Medical Devices | Used in the synthesis of neurosystem-related drugs | Specific structural motifs introduced via functional group transformations |
| Chemicals | Serves as a starting material for fine chemicals | Downstream compounds prepared through reactions such as esterification and acylation |
| Pesticides | Synthesized into chiral pesticide active ingredients | Benzylpyrrolidine scaffold incorporated to enhance selectivity and biological activity |
| Materials | Used to prepare chiral ligands or catalysts | Functionalized materials or catalyst precursors constructed leveraging the chiral center |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-220 nm, comparing peak area to reference standard. |
| Chiral Purity | Chiral HPLC | Separates enantiomers on a chiral stationary phase and quantifies (3R,4R) isomer relative to total stereoisomers. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric titration using iodine-based reagent reacting stoichiometrically with water. |
| Residual Solvents | GC-FID | Detects and quantifies volatile organic solvents (e.g., methanol, ethyl acetate) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni) via inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after combustion with sulfuric acid treatment and high-temperature ignition. |
| Optical Rotation | [alpha]D Measurement | Determines specific optical rotation using sodium D-line light source to confirm chiral integrity and enantiomeric excess. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., diastereomers, degradants) using gradient HPLC with UV detection. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine size distribution based on angular scattering intensity of laser light. |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtering sample through membrane, then culturing on tryptic soy agar under controlled conditions. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -33.6 ± 3.0° (c=1, in methanol) |
| Melting Point | 128–132°C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Identification (NMR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.