China Factory Direct
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| CAS number | 163444-17-5 |
| Product name | 4-Amino-3-iodobenzotrifluoride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing active pharmaceutical ingredients (APIs), including antitumor agents and kinase inhibitors | Constructs complex aromatic structures via transition metal-catalyzed reactions, such as Suzuki coupling and Buchwald-Hartwig amination |
| Agrochemicals | Used to synthesize novel high-efficacy, low-toxicity herbicides and fungicides containing fluorine or iodine | Introduces trifluoromethyl and iodine substituents onto aromatic rings to enhance biological activity and selectivity |
| Materials Science | Building block for organic optoelectronic materials, such as OLED emissive layer materials and liquid crystal molecules | Enables subsequent cross-coupling reactions via the iodine atom to fine-tune molecular energy levels and optoelectronic properties |
| Fine Chemicals | General intermediate for synthesizing high-value fluorinated aromatic compounds | Undergoes functional group transformations via nucleophilic substitution, halogen-metal exchange, or reductive deiodination |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 254 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities (e.g., isomers, dehalogenated by-products) via gradient HPLC-UV against qualified impurity standards. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., toluene, DMF, methanol) based on calibrated response factors. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent; water reacts stoichiometrically to determine trace moisture content. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, Hg, As) after acid digestion, using isotopic detection for high sensitivity and selectivity. |
| Iodine Content | Potentiometric Titration with Silver Nitrate | Titration with AgNO3 solution using a silver indicator electrode; endpoint detected by potential change due to AgI precipitation. |
| Acid-Base Impurities | Non-aqueous Acid-Base Titration | Titration in glacial acetic acid using perchloric acid as titrant and crystal violet indicator to determine basic impurities. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight; residue mass reflects inorganic ash content. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to determine volume-based particle size distribution in dry or wet dispersion. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary apparatus per USP <741>. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on anion-exchange column with suppressed conductivity detection, quantified against chloride standard. |
| Organic Volatile Impurities (OVI) | GC-MS | Targeted and untargeted screening of low-level volatile organic impurities using gas chromatography coupled with mass spectrometry detection. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65–69°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.