China Factory Direct
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| CAS number | 16357-59-8 |
| Product name | N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Coupling agent for peptide synthesis | Serves as an alternative coupling agent to carbodiimides (e.g., EDC) for amide bond formation between the carboxyl group of one amino acid and the amino group of another, minimizing racemization |
| Pharmaceutical Chemicals | Synthesis of pharmaceutical intermediates | Used in the synthesis of antibiotic intermediates, including cephalosporins and penicillins |
| Biochemistry | Protein sequencing and modification | Applied in carboxyl-group modification and fragment ligation reactions involving proteins or peptides |
| Organic Synthesis | Preparation of activated esters | Converts carboxylic acids into more reactive ester intermediates to facilitate subsequent nucleophilic substitution reactions |
| Research Reagents | Coupling reagent | Commonly employed in laboratory-scale solid-phase or solution-phase peptide synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-DAD | Identifies and quantifies impurities by retention time and UV spectral matching, using gradient elution and diode array detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., ethanol, ethyl acetate) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, As, Hg) after acid digestion by inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary tube method per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measures chiral purity by detecting rotation of plane-polarized light in solution at specified concentration and wavelength. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Evaluates acidity/basicity of saturated aqueous suspension using calibrated pH electrode and buffer standards. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample by measuring angular scattering intensity of laser beam to derive size distribution. |
| Bulk and Tapped Density | Tap Density Tester | Determines powder flowability and packing characteristics via standardized mechanical tapping and volumetric measurement. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (HPLC) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 124-128°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.