China Factory Direct
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| CAS number | 16357-69-0 |
| Product name | 4-AMINOPYRIMIDINE-5-CARBONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediate | Used in the synthesis of vitamin B1 (thiamine) and its derivatives, as well as antiviral and antitumor agents; serves as a key structural unit in functionalization reactions of the pyrimidine ring. |
| Agrochemicals | Agrochemical Intermediate | Applied in the synthesis of pyrimidine-based fungicides, herbicides, and plant growth regulators; functions primarily as a building block for constructing the pyrimidine heterocyclic scaffold. |
| Organic Synthesis | Organic Synthesis Building Block | Employed in cyclization, condensation, or nucleophilic substitution reactions—leveraging the reactivity of its amino and cyano groups—to construct complex fused heterocyclic compounds. |
| Scientific Research | Chemical and Biological Reagent | Utilized in enzyme inhibitor studies, structure–activity relationship (SAR) analysis, and laboratory-scale synthesis and development of novel heterocyclic compounds. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Detection and quantification of volatile organic solvents using gas chromatography with flame ionization detection and headspace sampling. |
| Water Content | Karl Fischer Titration | Electrochemical titration with iodine reagent to determine trace water based on the stoichiometric reaction between iodine, sulfur dioxide, water, and base. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for ultra-trace sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract; quantified against chloride standard calibration curve. |
| Sulfate Impurity | Ion Chromatography | Anion exchange separation followed by suppressed conductivity detection; quantified using sulfate reference standards. |
| Residue on Ignition | Gravimetric Analysis | Determination of non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing of the cooled crucible. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as the temperature range over which solid-to-liquid phase change occurs under controlled heating rate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles or discoloration against established reference standards under controlled lighting. |
| pH of Aqueous Suspension | pH Meter | Measurement of hydrogen ion activity in a defined suspension (e.g., 1% w/v in water) using calibrated pH electrode. |
| Bulk Density | Graduated Cylinder Method | Determination of mass per unit volume after gentle tapping of a known mass of sample in a calibrated cylinder to achieve settled volume. |
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 148-152°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.