China Factory Direct
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| CAS number | 163586-86-5 |
| Product name | Guanosine-9-17N, N-(2-methyl-1-oxopropyl)-, 2',3'-diacetate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Nucleoside-based antiviral drug intermediate | Used to synthesize modified guanosine derivatives with antiviral activity, such as prodrugs or active metabolites, via deprotection, phosphorylation, and related steps |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison with a certified reference standard using reversed-phase chromatography and UV detection at ~254 nm. |
| Related Substances | HPLC-UV/HRMS | Separation and identification of structurally related impurities (e.g., deacetylated, hydrolyzed, or isomeric forms) via retention time matching and high-resolution mass confirmation. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., acetone, acetonitrile, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration quantifying water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element trace metal quantification after acid digestion, using isotopic detection with ultra-low detection limits and matrix-matched calibration. |
| Residual Catalysts (e.g., Pd, Ni) | ICP-OES | Quantification of transition metal residues post-catalytic synthesis by plasma excitation and element-specific emission intensity measurement. |
| Optical Rotation | [α]D | Measurement of specific rotation using a polarimeter at 20 °C with sodium D-line (589 nm) to confirm chiral integrity and enantiomeric identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or dispersed solid sample via light scattering pattern to determine D10, D50, D90 values per ISO 13320. |
| Microbial Contamination | Membrane Filtration & Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus, P. aeruginosa) per USP <61> and <62>. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content after controlled high-temperature incineration (700–800 °C) and precise weighing of residual residue. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Measurement of hydrogen ion activity in a standardized aqueous suspension (e.g., 1% w/v) using calibrated pH electrode per USP <791>. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 178–182°C |
| Identification (NMR) | Conforms to reference standard |
| Optical Rotation | [α]D²⁰ = -25° to -35° (c = 1, in methanol) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.