Fmoc-D-Trp(Boc)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 163619-04-3 |
| Product name | Fmoc-D-Trp(Boc)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-D-Trp(Boc)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-D-Trp(Boc)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-D-Trp(Boc)-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Intermediate for synthesizing peptide-based drugs | Used as an amino-protecting group in solid-phase or solution-phase peptide synthesis to ensure defined stereochemistry |
| Organic Synthesis | Synthesis of compounds with specific stereochemistry | Enables site-selective modification of D-tryptophan via introduction of fluorenylmethyloxycarbonyl (Fmoc) and tert-butoxycarbonyl (Boc) protecting groups |
| Biopharmaceuticals | Development of novel antibiotics or bioactive molecules | Applied in peptide drug design to construct structures with targeted biological activity |
| Chemical Research | Reference standard for analytical testing | Used in chromatographic or spectroscopic analysis to confirm structural identity and purity of synthetic products |
Manufacturing Quality Control of Fmoc-D-Trp(Boc)-OH
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color, state, and presence of visible impurities in the sample. Typically appears as a white to off-white powder. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use reverse-phase HPLC (e.g., C18 column), with a UV detector at 220 nm or 254 nm. Calculate the purity of the main component by peak area; generally requires ≥98%. |
| Chiral Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Use chiral stationary phase columns to detect the ratio of D-configuration and L-configuration impurities, ensuring no contamination from L-isomers. |
| Water Content | Karl Fischer Titration | Determine the total amount of bound and free water in the sample to control its impact on stability; typically requires ≤0.5%. |
| Residual Solvents | Gas Chromatography (GC) | Detect residual organic solvents (e.g., DMF, ethyl acetate, dichloromethane) used during synthesis, complying with ICH guideline limits. |
| Content Determination | Titrimetry or HPLC External Standard Method | Determine the actual content of active ingredients through acid-base titration or HPLC comparison with standard samples. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range of the compound for preliminary assessment of purity and crystalline consistency. |
| UV Absorption Characteristics | UV-Visible Spectrophotometry (UV-Vis) | Exhibits characteristic absorption near 280 nm (due to indole ring), used for structural identification and auxiliary quantitative analysis. |
| Mass Spectrometry Analysis (Molecular Weight Confirmation) | Mass Spectrometry (MS, e.g., ESI-MS or MALDI-TOF) | Confirm the molecular ion peak of the target compound to verify whether the molecular weight matches the theoretical value (e.g., C₃₀H₃₄N₂O₆). |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR, ¹H & ¹³C) | Analyze the ¹H NMR and ¹³C NMR spectra to confirm the chemical structure, substituent positions, and stereochemical information. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Detect toxic metal residues such as lead, mercury, cadmium, and arsenic, complying with pharmacopoeia or GMP-related limit requirements. |
| Microbial Limits | Microbial Limit Test Method | Includes aerobic bacterial count, mold and yeast count, and controlled bacteria testing (e.g., Escherichia coli), applicable for pharmaceutical-grade products. |
Technical Specifications of Fmoc-D-Trp(Boc)-OH
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | +19.0° to +22.0° (c=1, in DMF) |
| Melting Point | 148°C to 152°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-D-Trp(Boc)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-D-Trp(Boc)-OH
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Industrial Fmoc-D-Trp(Boc)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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