China Factory Direct
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| CAS number | 16373-93-6 |
| Product name | 2'-Deoxyadenosine monohydrate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Used as a nucleoside analog in the synthesis of antiviral drugs | Derived from adenosine via chemical synthesis or enzymatic reaction, followed by deoxygenation and purification via hydration crystallization |
| Biotechnology | Used as a reference standard for DNA sequencing, PCR amplification, and molecular biology research | Prepared as high-purity crystals for instrument calibration and experimental system validation |
| Pharmaceutical R&D | Serves as a precursor in the synthesis of nucleoside-based anticancer or antiviral drugs | Obtained as a high-purity intermediate through protecting group modification, deoxygenation, and hydration crystallization |
| Diagnostics | Used as an internal standard or reference material in nucleic acid analysis | Purified by HPLC and lyophilized into a standard for quantitative PCR or mass spectrometry assays |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 260 nm. |
| Related Substances | HPLC-UV | Separation and detection of structurally related impurities (e.g., adenine, adenosine, deoxyadenosine derivatives) using gradient HPLC with UV detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of water with iodine, sulfur dioxide, and base in methanol/pyridine medium. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, ethanol, acetone) per ICH Q3C guidelines. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppq sensitivity. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous solution after sample dissolution and filtration. |
| Sulfate Content | Ion Chromatography | Separation and conductivity detection of sulfate ions following sample dissolution and dilution in water. |
| pH (1% w/v aqueous solution) | Potentiometric pH Measurement | Measurement of hydrogen ion activity using calibrated glass electrode in a 1% (w/v) aqueous solution at 25 C. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid material against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range over which the crystalline solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) following pharmacopeial procedures. |
| Residue on Ignition | Gravimetric Analysis | Weighing of inorganic residue remaining after charring and incineration at 700-800 C, indicating non-volatile inorganic impurities. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 178-182°C |
| Optical Rotation | -27.0 to -24.0° (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.