(R)-4-Boc-2-methylpiperazine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 163765-44-4 |
| Product name | (R)-4-Boc-2-methylpiperazine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (R)-4-Boc-2-methylpiperazine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (R)-4-Boc-2-methylpiperazine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (R)-4-Boc-2-methylpiperazine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a chiral intermediate in the synthesis of biologically active drug molecules, including antiviral, anticancer, and central nervous system agents | Integrated into multistep organic syntheses via deprotection (e.g., Boc removal), alkylation, or acylation to install the piperazine ring and construct the core scaffold of the target compound |
| Pharmaceutical R&D | Employed to build candidate compound libraries containing methylpiperazine motifs, supporting structure–activity relationship (SAR) studies | Used as a starting material in high-throughput synthesis or combinatorial chemistry, generating structurally diverse derivatives via nucleophilic substitution, reductive amination, and related reactions |
| Agrochemicals | Potentially applied in the synthesis of stereoselective pesticide active ingredients | Applied as a chiral building block in constructing heterocyclic pesticide molecules to enhance target selectivity and environmental safety |
Manufacturing Quality Control of (R)-4-Boc-2-methylpiperazine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Enantiomeric Excess (ee) | Chiral HPLC | Separation of (R)- and (S)-enantiomers on a chiral stationary phase, with UV detection and calculation of ee from peak area ratio. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents (e.g., THF, EtOAc, MeOH) using gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of iodine with water in a pyridine-methanol buffer. |
| Heavy Metals | ICP-MS | Multi-element detection and quantification of toxic metals (e.g., Pb, Cd, Hg, Ni) after acid digestion and dilution. |
| Chloride Impurity | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous solution after sample dissolution and filtration. |
| Residual Palladium | ICP-OES | Quantification of palladium from catalytic residues after microwave-assisted acid digestion and plasma emission measurement. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., de-Boc, N-oxide, diastereomers) using gradient HPLC-UV. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change under controlled heating rate; used for identity and purity screening. |
| Specific Optical Rotation | [alpha]D Measurement | Measurement of rotation of plane-polarized light at 589 nm to confirm chiral integrity and concentration-corrected enantiomeric identity. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under specified temperature and vacuum conditions to determine volatile content. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of foreign particles under controlled lighting and against standard references. |
Technical Specifications of (R)-4-Boc-2-methylpiperazine
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Optical Rotation | +14.0 to +18.0° (c=1, in methanol) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 78–82°C |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (R)-4-Boc-2-methylpiperazine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (R)-4-Boc-2-methylpiperazine
Packaging of (R)-4-Boc-2-methylpiperazine
Industrial (R)-4-Boc-2-methylpiperazine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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