TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 164331-38-8 |
| Product name | TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Key intermediate for synthesizing antitumor, antiviral, and CNS-targeted drugs (e.g., PARP inhibitors, S1P receptor modulators) | Used as a protecting group for the piperazine nitrogen atom in coupling reactions; deprotected with TFA/DCM prior to nucleophilic substitution with acyl chlorides, sulfonyl chlorides, or aryl halides; commonly employed in solid-phase or solution-phase multistep syntheses to protect nitrogen and ensure functional group compatibility |
| Fine Chemicals | Monomer precursor for novel functional materials containing sulfonylethylpiperazine motifs (e.g., ion-conductive polymers, metal ligands) | Methylsulfonyl group participates in nucleophilic substitution or transition-metal coordination; tert-butoxycarbonyl (Boc) provides reversible protection to enable subsequent selective modification |
| Agrochemical R&D | Structural building block for piperazine-containing sulfonamide insecticides/fungicides (e.g., candidates targeting insect GABA receptors or fungal chitin synthase) | After Boc deprotection, condensed with reactive haloarenes or heterocyclic compounds, followed by sulfonamidation or oxidation to optimize agrochemical activity |
Manufacturing Quality Control of TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210-230 nm. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC with UV detection; identification and quantification relative to main peak. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common organic solvents (e.g., THF, DCM, MeOH, EtOAc) based on retention time and calibration curves. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine water content via stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element trace metal analysis after acid digestion; detection based on mass-to-charge ratio and isotopic abundance. |
| Chloride Impurity | Ion Chromatography | Separation of anions on an ion-exchange column with suppressed conductivity detection for quantitative chloride determination. |
| Sulfate Impurity | Ion Chromatography | Anion exchange separation followed by conductivity detection to quantify sulfate ions in the sample solution. |
| Residual Palladium | ICP-MS | Post-digestion elemental analysis targeting Pd isotopes (e.g., 105Pd, 106Pd) for catalyst residue assessment. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20-25 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of solid-to-liquid transition range using calibrated capillary method per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed particles by measuring angular scattering intensity of laser light to derive size distribution. |
| Loss on Drying | Gravimetric Method | Weight loss measured after drying under controlled temperature and vacuum conditions per USP <731>. |
Technical Specifications of TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116 °C |
| Identification (NMR) | Conforms to reference spectrum |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE
Safety Information of TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE
Industrial TERT-BUTYL 4-(METHYLSULFONYL)PIPERAZINE-1-CARBOXYLATE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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