China Factory Direct
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| CAS number | 164365-88-2 |
| Product name | 4-(BOC-AMINO)BUTYL BROMIDE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
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| Pharmaceutical R&D | Intermediate for synthesizing nitrogen-containing heterocyclic drug molecules (e.g., GABA receptor modulators, kinase inhibitors) | Under inert atmosphere, undergoes N-alkylation, reductive amination, or cyclization with bases (e.g., NaH, K2CO3) and electrophiles (e.g., aldehydes, ketones, alkyl halides); typically requires low-temperature control and strict anhydrous conditions |
| Organic Synthesis | Multifunctional amino protecting/activating reagent, providing a cleavable tert-butoxycarbonyl (Boc) group and a bromobutyl side chain | Boc deprotection (TFA/DCM) yields the primary amine; the bromo terminus participates in SN2 substitutions (e.g., with sodium azide, thiols, amines) or palladium-catalyzed cross-couplings (e.g., Heck, Stille reactions) |
| Materials Science | Building block for pH-/light-responsive polymer precursors, used in smart hydrogels or drug delivery carriers | Initiates atom transfer radical polymerization (ATRP) via the bromo end group, or undergoes click coupling with multifunctional compounds (e.g., dithiols, diazides) to synthesize star-shaped or crosslinked polymers |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound using reversed-phase HPLC with UV detection at 210-230 nm, comparing peak area to reference standard calibration curve. |
| Related Substances | HPLC-UV | Detects and quantifies impurities (e.g., starting materials, dehalogenated byproducts) via gradient HPLC-UV against qualified reference standards. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, toluene) using headspace GC with flame ionization detection against internal standard calibration. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration using iodine generation in pyridine-free reagent system. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Residual Palladium | ICP-OES | Measures palladium catalyst residue post-hydrogenation using inductively coupled plasma optical emission spectroscopy with matrix-matched calibration. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid impurities by titration with standardized NaOH solution using phenolphthalein indicator. |
| Chloride Content | Ion Chromatography | Quantifies chloride ions from hydrolysis or salt residues using suppressed conductivity detection with sodium carbonate/bicarbonate eluent. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of neat sample against white/black background under controlled lighting per EP 2.2.1. |
| Specific Optical Rotation | Polarimetry | Determines chiral purity by measuring rotation of plane-polarized light at 589 nm using sodium D-line lamp and specified concentration/path length. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing per USP <281>. |
| Test Item | Specification |
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| Appearance | Off-white solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 52-56°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.