China Factory Direct
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| CAS number | 1645-65-4 |
| Product name | 4-(TRIFLUOROMETHYL)PHENYL ISOTHIOCYANATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticide intermediate | Used to synthesize trifluoromethyl-substituted phenyl isothiocyanate insecticidal compounds, such as structural modification units for pyrethroid or neonicotinoid derivatives |
| Pharmaceuticals | Pharmaceutical synthesis intermediate | Employed in constructing lead compounds containing the trifluoromethylphenyl isothiocyanate motif for molecular optimization of anticancer, anti-inflammatory, or antimicrobial drug candidates |
| Materials Science | Functional polymer monomer | Reacts with amine compounds via the isothiocyanate group to incorporate trifluoromethyl side chains, thereby modulating polymer hydrophobicity, thermal stability, and dielectric properties |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Separation and quantification of volatile organic solvents by equilibrium partitioning into headspace gas followed by GC analysis. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; endpoint detected amperometrically. |
| Acid Value | Acid-Base Titration with NaOH standard solution | Neutralization of acidic impurities (e.g., hydrolyzed isothiocyanate) using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element detection via ionization in plasma and mass-selective detection at isotopic masses; provides sub-ppt sensitivity. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled high-temperature ashing at 600-750 C and subsequent weighing. |
| Chloride Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column and quantitative detection via changes in electrical conductivity. |
| Related Substances | High-Performance Liquid Chromatography (HPLC) with UV detection | Separation of structurally similar impurities on a reversed-phase column and quantification using UV absorbance at 220-280 nm. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against specified criteria under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary tube method per USP <741>. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral impurities or degradation products in solution. |
| pH of Aqueous Solution | pH Meter Measurement | Electrochemical measurement of hydrogen ion activity in a saturated aqueous suspension using calibrated pH electrode. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 52–56°C |
| Identification (NMR) | Conforms to reference spectrum |
| Identification (IR) | Conforms to reference spectrum |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Danger |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.