China Factory Direct
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| CAS number | 16485-10-2 |
| Product name | Panthenol |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Applications | Processing |
|---|---|---|
| Cosmetics | Humectant, skin conditioning agent | Added to formulations such as lotions, creams, and serums to support skin hydration and repair |
| Pharmaceuticals | Wound healing promotion, treatment of skin inflammation | Formulated into topical preparations including ointments and sprays for local application |
| Hair care | Strengthening hair fibers, reducing breakage | Added to shampoos, conditioners, and hair masks to nourish the cuticle layer |
| Personal care | Relief of dryness and skin irritation | Used in infant care products and skincare formulations for sensitive skin |
| Nutritional supplements | Provitamin B5, supporting metabolic functions | Administered orally as capsules or tablets; metabolized in vivo to pantothenic acid for coenzyme A synthesis |
| Test Item | Common Test Method | Method Summary |
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| Identification | Infrared Spectroscopy (IR) | Compare the infrared absorption spectra of the sample and reference standard within the range of 4000–400 cm⁻¹; characteristic peaks should match. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically around 210 nm) to quantify DL-panthenol content by external or internal standard method. The mobile phase is commonly methanol-water or buffer solution. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Detect impurity peaks other than the main component using the same HPLC system, calculate individual and total impurity limits, and evaluate purity. |
| Specific Optical Rotation | Polarimetry | Although DL-panthenol is a racemic mixture (optically inactive), this test can confirm it is not a single optical isomer; D-panthenol is levorotatory, L-panthenol is dextrorotatory, and the DL-form shows rotation close to 0°. |
| Water Content | Karl Fischer Titration | Accurately determine water content using a Karl Fischer titrator; suitable for raw materials or cosmetic additives requiring strict moisture control. |
| pH Value | pH Meter Method | Dissolve in water to a specified concentration (e.g., 5% solution), then measure pH using a calibrated pH meter to control acidity or alkalinity within acceptable limits. |
| Residual Solvents | Gas Chromatography (GC) | Detect organic solvents possibly remaining from manufacturing (e.g., methanol, ethanol, acetone) according to ICH guidelines. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, measure levels of heavy metal elements such as lead, arsenic, mercury, and cadmium to ensure compliance with pharmacopoeial or cosmetic safety standards. |
| Sulfated Ash / Residue on Ignition | Residue on Ignition Test | Weigh the residue after high-temperature incineration of the sample to assess the total amount of inorganic impurities. |
| Microbial Limits | Microbial Limit Test | Perform tests for total aerobic microbial count, mold and yeast count, and specified microorganisms (e.g., Escherichia coli) according to the Chinese Pharmacopoeia or ISO standards. |
| Test Item | Specification |
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| Appearance | White solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 47–49°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Optical Rotation | -0.5° to +0.5° (c=1, H2O) |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.