Glycochenodeoxycholic acid sodium salt Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 16564-43-5 |
| Product name | Glycochenodeoxycholic acid sodium salt |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty GradeFood Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Glycochenodeoxycholic acid sodium salt
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Glycochenodeoxycholic acid sodium salt Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Glycochenodeoxycholic acid sodium salt
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used in the preparation of drugs for cholestatic liver disease, such as ursodeoxycholic acid analogs | Produced via chemical synthesis by coupling glycine with chenodeoxycholic acid, followed by purification to yield sodium glycochenodeoxycholate |
| Biotechnology | Employed as a surfactant in cell culture media to enhance cell membrane permeability and protein expression efficiency | Added to cell culture media at controlled concentrations to modulate the microenvironment and support cell growth and protein secretion |
| Chemical Intermediates | Served as an intermediate in the synthesis of other bile acid derivatives | Structurally modified via esterification, amidation, and related reactions to generate novel drug molecules |
| Food Additive (Limited Use) | Used as an emulsifier in select functional food products (subject to regulatory compliance) | Manufactured from high-purity raw materials under stringent process controls, with dosage carefully regulated to meet food safety standards |
Manufacturing Quality Control of Glycochenodeoxycholic acid sodium salt
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Identification Test | Infrared Spectroscopy (IR) | Determine the infrared absorption spectrum of the sample and compare it with standard spectra to confirm the characteristic functional groups and molecular structure of sodium glycocholate. |
| Identification Test | Thin Layer Chromatography (TLC) | Compare the sample with a reference under identical conditions by evaluating spot positions (Rf values) and coloration behavior for preliminary identification. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use a reverse-phase C18 column with an appropriate mobile phase (e.g., acetonitrile-water or methanol-buffer system) for isocratic or gradient elution. Quantify the main component using a UV detector at typically 200–210 nm wavelength. |
| Related Substances (Impurity Check) | High-Performance Liquid Chromatography (HPLC) | Similar conditions as content determination, but optimized separation parameters are used to effectively separate and detect potential impurities (e.g., free bile acids, other conjugated bile acids, degradation products), usually calculated by area normalization or main component self-comparison with correction factors. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Atmospheric Drying Method | Dry the sample at a specified temperature (e.g., 105°C) until constant weight is achieved, and determine the percentage of mass loss due to water or other volatile components. |
| Residue on Ignition | High-Temperature Incineration Method | Caramelize the sample and then incinerate it in a high-temperature furnace at 700–800°C to measure the weight of residual inorganic matter (ash), which reflects the level of inorganic impurities. |
| Heavy Metals | Thioglycolic Acid Method or Atomic Absorption Spectroscopy (AAS) | Detect total or individual levels of heavy metal elements (e.g., lead, arsenic, cadmium, mercury) using a colorimetric method (thioglycolic acid coloring) or instrumental methods (AAS/ICP-MS) to ensure compliance with pharmacopoeia limits. |
| pH Value | pH Meter Method | Prepare a solution of specific concentration (e.g., 1%) in water and measure its acidity or alkalinity using a calibrated pH meter to reflect product purity and potential acidic/basic impurities. |
| Optical Rotation | Polarimetry | Measure the optical rotation angle of a solution of defined concentration at a specific wavelength (typically sodium D line, 589 nm) using a polarimeter to verify the optical purity and identity of the compound. |
Technical Specifications of Glycochenodeoxycholic acid sodium salt
| Test Item | Specification |
|---|---|
| Appearance | White powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Optical Rotation | +9.0 to +9.5 (c=1, H2O) |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
| Identification (NMR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Glycochenodeoxycholic acid sodium salt
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Glycochenodeoxycholic acid sodium salt
Packaging of Glycochenodeoxycholic acid sodium salt
Industrial Glycochenodeoxycholic acid sodium salt Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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