China Factory Direct
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| CAS number | 165727-45-7 |
| Product name | (1S, 2S)-(1-BENZYL-3-CHLORO-2-HYDROXY-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Intermediate | Used in the synthesis of certain pharmaceutical compounds, including antiviral and anticancer agents. |
| Chemical Research | Research Tool | Employed as a chiral intermediate in organic synthesis to construct complex chiral molecular frameworks. |
| Materials Science | New Material Synthesis | Serves as a raw material for synthesizing novel polymeric materials, enabling the development of advanced materials with tailored properties. |
| Biotechnology | Biologically Active Molecule Synthesis | Acts as a key intermediate in the synthesis of biologically active molecules, enhancing product selectivity and yield. |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-220 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities (e.g., diastereomers, dechlorinated or hydrolyzed derivatives) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, ethyl acetate, toluene) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water by coulometric or volumetric titration with iodine generated electrochemically or added reagent, based on stoichiometric reaction with water. |
| Optical Purity (Enantiomeric Excess) | Chiral HPLC-UV | Resolves (1S,2S) enantiomer from (1R,2R), (1S,2R), and (1R,2S) diastereomers using chiral stationary phase and UV detection. |
| Heavy Metals | ICP-MS | Quantifies trace elements (Pb, Cd, Hg, As, Ni) after acid digestion by inductively coupled plasma mass spectrometry with isotopic detection. |
| Residual Palladium | ICP-MS | Specifically measures palladium residue from catalytic hydrogenation steps using isotope-dilution ICP-MS for high sensitivity and accuracy. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions via suppressed conductivity detection after aqueous extraction of sample. |
| Residual Benzyl Chloride | GC-MS | Identifies and quantifies unreacted benzyl chloride precursor by gas chromatography coupled with mass spectrometric detection. |
| Particle Size Distribution | Laser Diffraction | Measures dry powder particle size distribution using Mie scattering theory applied to laser light diffraction patterns. |
| Melting Point | DSC | Determines onset and range of melting transition by differential scanning calorimetry under controlled heating rate. |
| Appearance and Color | Visual Inspection / Hazen Scale | Assesses physical state (crystalline solid), color (by comparison to platinum-cobalt standards), and absence of visible particulates under controlled lighting. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 85°C to 89°C |
| Optical Rotation | +24.0° to +26.0° (c=1, in CHCl3) |
| Identification (NMR) | Conforms to reference standard |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.